Evidence map›Paper›PMID 22683929›Full record

ReviewNeuroscience and biobehavioral reviews2013

CNTRICS final animal model task selection: control of attention.

C Lustig, R Kozak, M Sarter, J W Young, T W Robbins

Abstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. EEG reveals that dextroamphetamine improves cognitive control through multiple processes in healthy participants.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
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  14. α4β2Annals of neurology · 2021
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  18. Review
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  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

C LustigDepartment of Psychology, University of Michigan, Ann Arbor, MI, USA. Electronic address: clustig@umich.edu.
R Kozak
M Sarter
J W Young
T W Robbins

Funding

Choline transporter capacity limits motivated behavior on mice, rats, and humansR01MH086530 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SARTER, MARTIN F · 2010 to 2014
$1.9M
Nicotinic regulation of cortical ACh release and behavioral functionR01MH080332 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SARTER, MARTIN F · 2007 to 2010
$1.2M
Medical Research Council G0001354Medical Research Council G1000183NIMH NIH HHS MH080332NIMH NIH HHS MH086530NIMH NIH HHS R01 MH080332NIMH NIH HHS R01 MH086530Wellcome Trust
6 · The paper itself

Abstract

Schizophrenia is associated with impaired attention. The top-down control of attention, defined as the ability to guide and refocus attention in accordance with internal goals and representations, was identified by the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative as an important construct for task development and research. A recent CNTRICS meeting identified three tasks commonly used with rodent models as having high construct validity and promise for further development: The 5-choice serial reaction time task, the 5-choice continuous performance task, and the distractor condition sustained attention task. Here we describe their current status, including data on their neural substrates, evidence for sensitivity to neuropharmacological manipulations and genetic influences, and data from animal models of the cognitive deficits of schizophrenia. A common strength is the development of parallel human tasks to facilitate connections to the neural circuitry and drug development research done in these animal models. We conclude with recommendations for the steps needed to improve testing so that it better represents the complex biological and behavioral picture presented by schizophrenia.

Indexed as

Disease Models, AnimalAnimalsAttention Deficit Disorder with HyperactivityCognition DisordersHumansNeuropsychological TestsSchizophrenia5C-CPT5CSRTTAttentionCNTRICSCognitive controldSATSchizophreniaTop-down attention

Identifiers

PMID22683929
PMCPMC3490036

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.