Trial reportThe American journal of geriatric pharmacotherapy2012
The impact of family caregivers on potentially inappropriate medication use in noninstitutionalized older adults with dementia.
Trial report in The American journal of geriatric pharmacotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 4 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Factors Associated with Psychotropic Medication Use in People Living with Dementia in the Community: A Systematic Review and Meta-Analysis.Drugs & aging · 2023Pooled it
- Global prevalence of polypharmacy and potentially inappropriate medication in older patients with dementia: a systematic review and meta-analysis.Frontiers in pharmacology · 2023Pooled it
- Interventions at Hospital Discharge to Guide Caregivers in Medication Management for People Living with Dementia: a Systematic Review.Journal of general internal medicine · 2021Pooled it
- Identifying potentially inappropriate prescribing in older people with dementia: a systematic review.European journal of clinical pharmacology · 2019Pooled it
- Patient-Family Agenda Setting for Primary Care Patients with Cognitive Impairment: the SAME Page Trial.Journal of general internal medicine · 2018Trial
- Household Wealth and Potentially Inappropriate Medications in Persons With Dementia: Role of Comorbidities and Caregivers.Journal of the American Geriatrics Society · 2025Article
- Practical strategies for improving medication management during care transitions for older adults with dementia: findings from a novel stakeholder-informed review process.Age and ageing · 2025Article
- Article
- Initiation and Persistence of Antipsychotic Medications at Hospital Discharge Among Community-Dwelling Veterans With Dementia.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025Article
- Aligning Medications With What Matters Most: Conversations Between Pharmacists, People With Dementia, and Care Partners.Journal of the American Geriatrics Society · 2025Article
- Receipt of Medicare Part D comprehensive medication reviews in older adults with dementia.Journal of managed care & specialty pharmacy · 2025Article
- Resigned but Resilient: Caregiver Perceptions of Role Ambiguity and Quality of Care During Hospital-to-Home Transitions of Older Latinos Living With Dementia.Journal of aging and health · 2025Article
- Improving How Caregivers of People Living With Dementia Are Identified in the Electronic Health Record: Qualitative Study and Exploratory Chart Review.JMIR aging · 2024Article
- Use of the Patient Portal to Discuss Medications Among People with Dementia and Their Care Partners.Journal of general internal medicine · 2024Article
- Mapping racial and ethnic healthcare disparities for persons living with dementia: A scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Medication exposure of the dyad patient-caregiver in Alzheimer's disease and related dementias: a cross-sectional study.International journal of clinical pharmacy · 2024Article
- A need to integrate pharmacological management for multimorbidity into dementia guidelines in Australia.Frontiers in public health · 2024Review
- Deprescribing research in nursing home residents using routinely collected healthcare data: a conceptual framework.BMC geriatrics · 2023Review
- Impact of pharmaceutical care integrated at a psychosocial intervention to reduce caregiver's burden in Alzheimer's disease or related dementias: Negative results at 18 months and difficulties to conduct PHARMAID RCT.Contemporary clinical trials communications · 2023Article
- Helping the Helpers - A research protocol for user-centered technology to aid caregiver management of medications for people with Alzheimer's disease and related dementias.Research in social & administrative pharmacy : RSAP · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe risk of potentially inappropriate medication (PIM), both prescription and over-the-counter, use in dementia patients is high. Informal caregivers often facilitate patients' use of medications, but the effect of caregiver factors on PIM use has not been a focus of previous research.
objectiveThe aim of this study was to examine PIM use in dementia patients and caregivers and identify caregiver risk factors for PIM use in dementia patients.
methodsWe conducted a secondary data analysis of the baseline wave of the Resources for Enhancing Alzheimer's Caregiver's Health study. The sample comprised 566 persons with dementia aged 65 and older and their coresiding family caregiver. PIM was defined using the 2003 Beers criteria and was examined in both dementia patients and their caregivers. Caregiver and patient risk factors included a range of sociodemographic and health variables.
resultsIn dementia patients, 33% were taking at least 1 PIM, and 39% of their caregivers were also taking a PIM. In fully adjusted models, the following caregiver factors were associated with an increased risk of dementia patient PIM use: caregiver's own PIM use, spouse caregivers, Hispanic caregivers, and greater number of years that the caregiver has lived in the United States. Increased caregiver age was associated with a decreased risk of PIM use in patients.
conclusionsPIM use may be higher in dementia patients and their informal caregivers compared with the general older adult population. Further, patterns of medication use in 1 member of the dyad may influence PIM risk in the other dyad member. These results suggest that interventions to increase appropriate medication use in dementia patients and their caregivers should target both members of the dyad and target over-the-counter agents along with prescription medications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.