Evidence map›Paper›PMID 22683074›Full record

ArticleThe Journal of surgical research2013

Comorbidity-polypharmacy score: a novel adjunct in post-emergency department trauma triage.

Carla F Justiniano, David C Evans, Charles H Cook, Daniel S Eiferman, Anthony T Gerlach, Paul R Beery, David E Lindsey, Gary E A Saum, Claire V Murphy, Sidney F Miller and 3 more

Abstract read
In one paragraph

Article in The Journal of surgical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Major trauma and comorbidity: a scoping review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  2. Article
  3. Comorbidities, injury severity and complications predict mortality in thoracic trauma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  4. Article
  5. Article
  6. Which pre-hospital triage parameters indicate a need for immediate evaluation and treatment of severely injured patients in the resuscitation area?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2019
    Article
  7. Article
  8. Article
  9. Portable ultrasound in disaster triage: a focused review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2016
    Review
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Carla F JustinianoDivision of Critical Care, Trauma, and Burn, Department of Surgery, The Ohio State University Medical Center, Columbus, OH 43210, USA.
David C Evans
Charles H Cook
Daniel S Eiferman
Anthony T Gerlach
Paul R Beery
David E Lindsey
Gary E A Saum
Claire V Murphy
Sidney F Miller
Thomas J Papadimos
Steven M Steinberg
Stanislaw P A Stawicki

Funding

The Ohio State University Center for Clinical and Translational Science (UL1)UL1TR000090 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2012 to 2013
$7.9M
NCATS NIH HHS UL1 TR000090
6 · The paper itself

Abstract

objectivePost-emergency department triage of older trauma patients continues to be challenging, as morbidity and mortality for any given level of injury severity tend to increase with age. The comorbidity-polypharmacy score (CPS) combines the number of pre-injury medications with the number of comorbidities to estimate the severity of comorbid conditions. This retrospective study examines the relationship between CPS and triage accuracy for older (≥45y) patients admitted for traumatic injury.

methodsPatients aged 45y and older presenting to level 1 trauma center from 2005 to 2008 were included. Basic data included patient demographics, injury severity score, morbidity and mortality, and functional outcome measures. CPS was calculated by adding total numbers of comorbid conditions and pre-injury medications. Patients were divided into three triage groups: undertriage (UT), appropriate triage (AT), and overtriage (OT). UT criteria included initial admission to the floor or step-down unit followed by an unplanned transfer to intensive care unit (ICU) within 24h of admission. OT was defined as initial ICU admission for <1d without stated need for ICU level of care (i.e., lack of evidence for tracheal intubation or mechanical ventilation, injury-related hemorrhage, or other traditional ICU indications, such as intracranial bleeding). All other patients were presumed to be correctly triaged. The three triage groups were then analyzed looking for contributors to mistriage.

resultsCharts for 711 patients were evaluated (mean age, 63.5y; 55.7% male; mean ISS, 9.02). Of those, 11 (1.55%) met criteria for UT and 14 (1.97%) for OT. The remaining 686 patients had no evidence of mistriage. The three groups were similar in terms of injury severity and GCS. The groups were significantly different with respect to CPS, with UT CPSs (14.9±6.80) being nearly three times higher than OT CPSs (5.14±3.48). There were more similarities between AT and OT groups, with the UT group being characterized by greater number of complications and lower functional outcomes at discharge (all, P<0.05). The UT group had significantly higher mortality (27%) than the AT and OT groups (6% and 0%, respectively).

conclusionsIn the era of medication reconciliation, CPS is easy to obtain and calculate in patients who are not critically injured. This study suggests that CPS may be a promising adjunct in identifying older trauma patients who are more likely to be undertriaged. The significance of our findings is especially important when considering that injury severity in the UT group was similar to that in the other groups. Further evaluation of CPS as a triage tool in acute trauma is warranted.

Indexed as

PolypharmacyTriageComorbidityFemaleHumansIntensive Care UnitsMaleMiddle AgedRetrospective Studies

Identifiers

PMID22683074
PMCPMC3717608

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.