ArticleThe Biochemical journal1990
Increased association of ribosomes with myofibrils during the skeletal-muscle hypertrophy induced either by the beta-adrenoceptor agonist clenbuterol or by tenotomy.
Article in The Biochemical journal, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- The skeletal muscle fiber periphery: A nexus of mTOR-related anabolism.Sports medicine and health science · 2023Review
- Translocation and protein complex co-localization of mTOR is associated with postprandial myofibrillar protein synthesis at rest and after endurance exercise.Physiological reports · 2018Article
- Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle.Scientific reports · 2017Article
- Fragile hearts: new insights into translational control in cardiac muscle.Trends in cardiovascular medicine · 2013Review
- Emerging role for the cytoskeleton as an organizer and regulator of translation.Nature reviews. Molecular cell biology · 2010Review
- RNA-protein interactions of the 3' untranslated regions of myosin heavy chain transcripts.Journal of muscle research and cell motility · 2002Article
- Clenbuterol-induced fiber type transition in the soleus of adult rats.European journal of applied physiology and occupational physiology · 1996Article
- Translation and the cytoskeleton: a mechanism for targeted protein synthesis.Molecular biology reports · 1994Review
- Ribosome distribution in normal and infarcted rat hearts.The Histochemical journal · 1994Article
- Myosin heavy-chain mRNA is present in both myofibrillar and subsarcolemmal regions of muscle fibres.The Biochemical journal · 1991Article
- Interaction between mRNA, ribosomes and the cytoskeleton.The Biochemical journal · 1991Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ribosome distribution in skeletal-muscle myofibres was investigated by immunohistochemistry and microdensitometry by using anti-(60 S ribosomal subunit) antibodies. Administration of the beta-adrenoceptor agonist clenbuterol caused an increase in the staining of the myofibrillar region with this antibody relative to that found in the subsarcolemmal cytoplasm. A similar effect was observed during hypertrophy of the plantaris muscle following severance of the tendon to the gastrocnemius. The results suggest that increased association of ribosomes with the myofibrils occurs during muscle hypertrophy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.