Trial reportSchizophrenia research2012
Computer-assisted cognitive remediation for schizophrenia: a randomized single-blind pilot study.
Trial report in Schizophrenia research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy of technology-based interventions in psychosis: a systematic review and network meta-analysis.Psychological medicine · 2023Pooled it
- Influence of placebo effect in mental disorders research: A systematic review and meta-analysis.European journal of clinical investigation · 2022Pooled it
- A systematic review on improving cognition in schizophrenia: which is the more commonly used type of training, practice or strategy learning?BMC psychiatry · 2014Pooled it
- Who will benefit from computerized cognitive remediation therapy? Evidence from a multisite randomized controlled study in schizophrenia.Psychological medicine · 2020Trial
- Impact of baseline early auditory processing on response to cognitive remediation for schizophrenia.Schizophrenia research · 2019Trial
- Evaluation of a plasticity-based cognitive training program in schizophrenia: Results from the eCaesar trial.Schizophrenia research · 2019Trial
- Supplementing intensive targeted computerized cognitive training with social cognitive exercises for people with schizophrenia: An interim report.Psychiatric rehabilitation journal · 2017Trial
- Neuroplasticity-based auditory training via laptop computer improves cognition in young individuals with recent onset schizophrenia.Schizophrenia bulletin · 2015Trial
- Randomized trial of self-adaptive computerized cognitive remediation in schizophrenia.NPJ digital medicine · 2026Article
- Enhanced computerized cognitive remediation therapy improved cognitive function, negative symptoms, and GDNF in male long-term inpatients with schizophrenia.Frontiers in psychiatry · 2024Article
- Advances in Cognitive Remediation Training in Schizophrenia: A Review.Brain sciences · 2022Review
- Cognitive Remediation in Virtual Environments for Patients with Schizophrenia and Major Depressive Disorder: A Feasibility Study.International journal of environmental research and public health · 2021Article
- Evaluation of a computer-assisted cognitive remediation program for young people with psychosis: A pilot study.Schizophrenia research. Cognition · 2021Article
- Quantifying the Difference between Active and Passive Control Groups in Cognitive Interventions Using two Meta-Analytical Approaches.Journal of cognitive enhancement : towards the integration of theory and practice · 2020Article
- Training engagement, baseline cognitive functioning, and cognitive gains with computerized cognitive training: A cross-diagnostic study.Schizophrenia research. Cognition · 2020Article
- Application and Effectiveness of Telehealth to Support Severe Mental Illness Management: Systematic Review.JMIR mental health · 2018Review
- Visual perceptual remediation for individuals with schizophrenia: Rationale, method, and three case studies.Psychiatric rehabilitation journal · 2017Article
- A survey of eMedia-delivered interventions for schizophrenia used in randomized controlled trials.Neuropsychiatric disease and treatment · 2017Article
- Aerobic Exercise in People with Schizophrenia: Neural and Neurocognitive Benefits.Current behavioral neuroscience reports · 2016Article
- Neural correlates of cognitive improvements following cognitive remediation in schizophrenia: a systematic review of randomized trials.Socioaffective neuroscience & psychology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Cognitive impairment is a core symptom in schizophrenia that has a significant impact on psychosocial function, but shows a weak response to pharmacological treatment. Consequently, a variety of cognitive remediation strategies have been evaluated to improve cognitive function in schizophrenia. The efficacy of computer-based cognitive remediation as a stand-alone intervention on general measures of neuropsychological function remains unclear. We tested the effectiveness of biweekly training using computerized cognitive remediation programs on neuropsychological and event-related potential outcome measures. Schizophrenia patients were randomly assigned to cognitive remediation training (N=17), active control (TV-watching; N=17), or treatment-as-usual (N=10) groups for ten weeks and run in parallel. Cognitive and ERP measures revealed no differential improvement over time in the cognitive remediation group. Practice effects might explain change over time on several cognitive measures for all groups, consistent with studies indicating task-specific improvement. Computer-assisted cognitive remediation alone may not be sufficient for robust or generalized effects on cognitive and electrophysiological measures in schizophrenia patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.