Evidence map›Paper›PMID 22681683›Full record

ReviewNeuron2012

Concepts and methods for the study of axonal regeneration in the CNS.

Mark H Tuszynski, Oswald Steward

Abstract readReview
In one paragraph

Review in Neuron, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 156 papers.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

156 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Astrocytic Ryk signaling coordinates scarring and wound healing after spinal cord injury.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Regenerative medicine.Journal of translational medicine · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mark H TuszynskiDepartment of Neurosciences, University of California, San Diego, La Jolla, CA 92093-0662, USA. mtuszynski@ucsd.edu
Oswald Steward

Funding

Plasticity and Regeneration in the Primate Spinal CordR01NS042291 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRESNAHAN, JACQUELINE C, CAPITANIO, JOHN P · 2001 to 2015
$13.0M
Combinatorial Approaches to SCIR01NS049881 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TUSZYNSKI, MARK H. · 2004 to 2008
$2.7M
NINDS NIH HHS R01 NS042291NINDS NIH HHS R01 NS049881
6 · The paper itself

Abstract

Progress in the field of axonal regeneration research has been like the process of axonal growth itself: there is steady progress toward reaching the target, but there are episodes of mistargeting, misguidance along false routes, and connections that must later be withdrawn. This primer will address issues in the study of axonal growth after central nervous system injury in an attempt to provide guidance toward the goal of progress in the field. We address definitions of axonal growth, sprouting and regeneration after injury, and the research tools to assess growth.

Indexed as

Central Nervous System DiseasesAnimalsAxonsCentral Nervous SystemHumansNerve Regeneration

Identifiers

PMID22681683
PMCPMC3387806

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.