Evidence map›Paper›PMID 22680764›Full record

ArticleLeukemia & lymphoma2013

High expression of neutrophil elastase predicts improved survival in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.

Chelsea J Gudgeon, Kimberly H Harrington, George S Laszlo, Todd A Alonzo, Robert B Gerbing, Alan S Gamis, Susana C Raimondi, Betsy A Hirsch, Soheil Meshinchi, Roland B Walter

Registry-linked trialOpen access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia & lymphoma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00070174 (Treatment of Newly Diagnosed Childhood Acute Myeloid Leukemia), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00070174 phase2completednot on this map

Treatment of Newly Diagnosed Childhood Acute Myeloid Leukemia (AML) Using Intensive MRC-Based Therapy and Gemtuzumab Ozogamicin (GMTZ): A COG Pilot Study

TypeinterventionalSponsorChildren's Oncology GroupRan2003 to 2013Enrolled350ConditionsLeukemiaArmsasparaginase, busulfan, cyclophosphamide, cyclosporine, cytarabine
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Chelsea J Gudgeon
Kimberly H Harrington
George S Laszlo
Todd A Alonzo
Robert B Gerbing
Alan S Gamis
Susana C Raimondi
Betsy A Hirsch
Soheil Meshinchi
Roland B Walter
Fred Hutch Cancer Center · USArcadia · USChildren's Oncology Group · CHChildren's Oncology Group · US

Funding

COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
NCI NIH HHS P30 CA015704NCI NIH HHS U10 CA098543
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene ExpressionAdolescentChildChild, PreschoolFemaleHumansInfantLeukemia, Myeloid, AcuteLeukocyte ElastaseMalePrognosisYoung AdultLeukocyte Elastase

Identifiers

PMID22680764
PMCPMC3757129
OpenAlexW2144338469

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.