Trial reportAJNR. American journal of neuroradiology2012
Safety of the pipeline embolization device in treatment of posterior circulation aneurysms.
Trial report in AJNR. American journal of neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 8 syntheses or guidelines pooled it, 206 citations in OpenAlex.
- Management strategies and outcomes of basilar trunk aneurysms: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2026Pooled it
- Flow-Diverting Devices in the Treatment of Vertebral Artery Aneurysms: Insights into Efficacy and Safety from a Systematic Review and Meta-analysis.Translational stroke research · 2025Pooled it
- Flow Diversion of Posterior Circulation Aneurysms: Systematic Review of Disaggregated Individual Patient Data.AJNR. American journal of neuroradiology · 2021Pooled it
- Efficacy and safety of flow diverters in posterior circulation aneurysms and comparison with their efficacy in anterior circulation aneurysms: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Pooled it
- Comparison between stenting and conservative management of posterior circulation perforator aneurysms: Systematic review and case series.Neuroradiology · 2021Pooled it
- Flow diverter treatment of posterior circulation aneurysms. A meta-analysis.Neuroradiology · 2016Pooled it
- Delayed hemorrhagic complications after flow diversion for intracranial aneurysms: a literature overview.Neuroradiology · 2016Pooled it
- Endovascular treatment of cerebral aneurysms using flow-diverter devices: A systematic review.The neuroradiology journal · 2015Pooled it
- Trial
- Modeling Perforator Occlusion After Flow Diversion.International journal for numerical methods in biomedical engineering · 2026Article
- Safety and hemodynamic efficacy of the LVIS stent in the endovascular treatment of intracranial wide-necked aneurysms: a single-center retrospective study.Chinese neurosurgical journal · 2026Article
- Endovascular treatment of posterior circulation aneurysms with flow diverters with hydrophilic polymer coating in patients receiving prasugrel single antiplatelet therapy: a multicenter case series presenting complication and occlusion rates.Journal of neurointerventional surgery · 2026Article
- Early Flow-Diverter Implantation in Ruptured Intracranial Aneurysms: Safety and Outcomes in a Resource-Limited Setting.Neurointervention · 2026Article
- Flow diversion versus conventional endovascular treatment for ruptured basilar artery dissecting aneurysms: a single-center cohort study.Frontiers in neurology · 2026Article
- Patency of the lenticulostriate and Pontine arteries after stenting of the intracranial arteries.Neurosurgical review · 2025Article
- Subgroup analysis of pipeline Flow-Diverter devices in the treatment of intracranial aneurysms: A long-term real-world study involving 190 patients.Neurosurgical review · 2025Article
- Indirect flow diversion for the treatment of saccular posterior inferior cerebellar artery aneurysms: An 11-year single-center retrospective study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Symptoms, Imaging Features, Treatment Decisions, and Outcomes of Patients with Top of the Basilar Artery Syndrome: Experiences from a Comprehensive Stroke Center.Neurocritical care · 2025Article
- Thalamo-mesencephalic Branches of the Posterior Cerebral Artery: a 3D Rotational Angiography Study.Clinical neuroradiology · 2024Article
- Analysis of reported adverse events of pipeline stents for intracranial aneurysms using the FDA MAUDE database.Journal of cerebrovascular and endovascular neurosurgery · 2023Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe published results of treating internal carotid artery aneurysms with the PED do not necessarily apply to its use in the posterior circulation because disabling brain stem infarcts can be caused by occlusion of a single perforator. In this multicenter study, we assessed the safety of PED placement in the posterior circulation. MATERIALS AND
methodsA prospective case registry was maintained of all posterior circulation aneurysms treated with PEDs at 3 Australian neurointerventional centers during a 27-month period. The objective was to assess the complications and aneurysm occlusion rates associated with posterior circulation PEDs.
resultsThirty-two posterior circulation aneurysms were treated in 32 patients. No deaths or poor neurologic outcomes occurred. Perforator territory infarctions occurred in 3 (14%) of the 21 patients with basilar artery aneurysms, and in all 3, a single PED was used. Two asymptomatic intracranial hematomas were recorded. No aneurysm rupture or PED thrombosis was encountered. The overall rate of permanent neurologic complications was 9.4% (3/32); all 3 patients had very mild residual symptoms and a good clinical outcome. Aneurysm occlusion was demonstrated in 85% of patients with >6 months of follow-up and 96% of patients with >1 year of follow-up.
conclusionsThe PED is effective in the treatment of posterior circulation aneurysms that are otherwise difficult or impossible to treat with standard endovascular or surgical techniques, and its safety is similar to that of stent-assisted coiling techniques. A higher clinical perforator infarction rate may be associated with basilar artery PEDs relative to the internal carotid artery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.