SynthesisJournal of neural transmission (Vienna, Austria : 1996)2012
Neuroimaging of cognitive brain function in paediatric obsessive compulsive disorder: a review of literature and preliminary meta-analysis.
Synthesis in Journal of neural transmission (Vienna, Austria : 1996), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Global trends and research hotspots in the treatment of mental disorders with transcranial magnetic stimulation: a bibliometric analysis.Frontiers in psychiatry · 2025Pooled it
- Inhibitory control in obsessive compulsive disorder: A systematic review and activation likelihood estimation meta-analysis of functional magnetic resonance imaging studies.NeuroImage. Clinical · 2022Pooled it
- Parent- and child-reported executive functioning and response to psychotherapy in pediatric obsessive-compulsive disorder: Results from the TECTO study.European child & adolescent psychiatry · 2026Article
- Article
- Will Transcranial Magnetic Stimulation Improve the Treatment of Obsessive-Compulsive Disorder? A Systematic Review and Meta-Analysis of Current Targets and Clinical Evidence.Life (Basel, Switzerland) · 2023Review
- Case report: Co-occurring autism spectrum disorder (Level One) and obsessive-compulsive disorder in a gender-diverse adolescent.Frontiers in psychiatry · 2023Article
- Preliminary Observations of Resting-State Magnetoencephalography in Nonmedicated Children with Obsessive-Compulsive Disorder.Journal of child and adolescent psychopharmacology · 2022Article
- Article
- Obsessive-Compulsive Symptoms Among Children in the Adolescent Brain and Cognitive Development Study: Clinical, Cognitive, and Brain Connectivity Correlates.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
- Visuomotor Activation of Inhibition-Processing in Pediatric Obsessive Compulsive Disorder: A Magnetoencephalography Study.Frontiers in psychiatry · 2021Article
- Serotonin system gene variants and regional brain volume differences in pediatric OCD.Brain imaging and behavior · 2020Article
- Pediatric OCD in the era of RDoC.Journal of obsessive-compulsive and related disorders · 2019Article
- Neural correlates of symptom provocation in pediatric obsessive-compulsive disorder.NeuroImage. Clinical · 2019Article
- Functional and Structural Neural Changes in Obsessive-compulsive Disorder after Pharmacotherapy.Current neuropharmacology · 2019Review
- Multivariate resting-state functional connectivity predicts response to cognitive behavioral therapy in obsessive-compulsive disorder.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Increased decision thresholds trigger extended information gathering across the compulsivity spectrum.Translational psychiatry · 2017Article
- Shared and Disorder-Specific Neurocomputational Mechanisms of Decision-Making in Autism Spectrum Disorder and Obsessive-Compulsive Disorder.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Comparison of neural substrates of temporal discounting between youth with autism spectrum disorder and with obsessive-compulsive disorder.Psychological medicine · 2017Article
- Cool and Hot Aspects of Executive Function in Childhood Obsessive-Compulsive Disorder.Journal of abnormal child psychology · 2017Article
- Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD).PLoS computational biology · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obsessive compulsive disorder (OCD) is a frequent psychiatric disorder with a prevalence of 1-3 %, and it places an enormous burden on patients and their relatives. Up to 50 % of all cases suffer from onset in childhood or adolescence, and the disorder often takes a chronic course with a poor long-term prognosis. Paediatric OCD, with its high familiality, is often referred to as a distinct OCD subtype that coincides with a developmental period in which the prefrontal cortex exhibits extensive structural and functional maturation. In the present review, we included all studies examining cognitive brain activation in children and/or adolescents with OCD. We conducted extensive literature searches for relevant articles (Pubmed, ScienceDirect) and summarize, tabulate, and discuss their results. For the eight activation studies using functional magnetic resonance imaging, we also performed preliminary meta-analyses to assess the most consistent hypo- and hyperactivation in paediatric OCD patients during cognitive task performance. The review of literature as well as our preliminary meta-analyses of paediatric studies indicated altered functional activation in the same brain regions of affective and cognitive cortico-striatal-thalamic (CST) circuits as for adult OCD patients despite some variations in the direction of activation difference. The still small number of studies that examined brain activation in paediatric OCD patients thereby largely converged with previous findings in adult patients and with the established neurobiological models of CST circuit dysfunction in OCD.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.