Evidence map›Paper›PMID 22678458›Full record

ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2012

Treatment for co-occurring attention deficit/hyperactivity disorder and autism spectrum disorder.

Naomi Ornstein Davis, Scott H Kollins

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03337646 phase4completednot on this mapstarted 2018, after this paper: background citation

A Multi-Center, Open Label, Evaluation of the Effect and Safety of Lisdexamfetamine in Children Aged 6-12 With Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder

TypeinterventionalSponsorJPM van Stralen Medicine ProfessionalRan2018 to 2023Enrolled48ConditionsAttention Deficit Hyperactivity Disorder, Autism Spectrum DisorderArmsLisdexamfetamine Dimesylate
NCT06303791 nacompletednot on this mapstarted 2022, after this paper: background citation

Digital-based Psychosocial Intervention for Parents of Children With Neurodevelopmental Disorders: a Randomized Control Trial

TypeinterventionalSponsorUniversity of ValenciaRan2022 to 2024Enrolled90ConditionsAutism Spectrum Disorder, Attention Deficit Hyper ActivityArmsDigital Psychosocial intervention
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Cumulative Adverse Childhood Experiences and Multiple Neurodevelopmental Disorders in Children and Adolescents: A Population-Based Study.Stress and health : journal of the International Society for the Investigation of Stress · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Naomi Ornstein DavisDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2608 Erwin Rd., Pavilion East, Suite 300, Durham, NC 27705, USA. naomi.davis@duke.edu
Scott H Kollins

Funding

Smoking/Nicotine Dependence in Attention Deficit Hyperactivity Disorder (ADHD)K24DA023464 · NIDA · DUKE UNIVERSITY · PI KOLLINS, SCOTT H · 2008 to 2018
$1.5M
NIDA NIH HHS K24 DA023464
6 · The paper itself

Abstract

Interest in the co-occurrence of attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) has grown in the last decade. Research on clinical populations supports the frequent co-occurrence of ADHD traits (e.g., hyperactivity) in individuals with ASD and ASD traits (e.g., social communication deficits) in individuals with ADHD. Similar trends in co-occurring traits have been observed in population-based samples, as well as family and genetic studies of affected individuals. Despite increased interest in co-occurring ADHD and ASD, relatively little research has been devoted to treatment considerations. The vast majority of intervention research has examined pharmacological treatment using traditional ADHD medications. Relatively few psychosocial interventions have directly addressed co-occurring symptoms. Treatment development will benefit from enhanced understanding of the phenomenon of co-occurring ADHD and ASD. Key topics for future research include examining developmental trajectories of co-occurring disorders, comorbid psychiatric conditions, deficits in social skills, and the nature of executive functioning impairment in individuals with co-occurring ADHD and ASD. In the current review, research in these areas is reviewed along with recommendation for future study. Given that clinicians are routinely observing and treating individuals with co-occurring symptoms, further research will yield needed information to inform intervention development and maximize benefits for affected individuals.

Indexed as

Attention Deficit Disorder with HyperactivityBiomedical ResearchChildChild Development Disorders, PervasiveHumans

Identifiers

PMID22678458
PMCPMC3441928

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.