ArticleBreast cancer research and treatment2012
Sentinel lymph node biopsy of the internal mammary chain in breast cancer.
Article in Breast cancer research and treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Should internal mammary lymph node sentinel biopsy be performed in breast cancer: a systematic review and meta-analysis.World journal of surgical oncology · 2019Pooled it
- The Clinical Impact of the Surgical Removal of the Internal Mammary Chain Sentinel Node in Breast Cancer Patients: Do We Need to De-Escalate our Former Strategy?Annals of surgical oncology · 2026Article
- ASO Author Reflections: De-Escalating Internal Mammary Sentinel Node Surgery in Breast Cancer.Annals of surgical oncology · 2026Article
- Internal mammary lymph node metastasis in breast cancer patients based on anatomical imaging and functional imaging.Breast cancer (Tokyo, Japan) · 2022Review
- Internal Mammary Sentinel Lymph Node Biopsy in Clinically Axillary Lymph Node-Positive Breast Cancer: Diagnosis and Implications for Patient Management.Annals of surgical oncology · 2020Article
- Multidisciplinary treatment for locally advanced breast cancer with internal mammary lymph node metastasis in an elderly patient.International cancer conference journal · 2019Article
- Internal mammary lymph node metastases in breast cancer: what should radiologists know?Japanese journal of radiology · 2018Review
- Article
- Internal mammary lymph nodes radiotherapy of breast cancer in the era of individualized medicine.Oncotarget · 2017Review
- Validation study for the hypothesis of internal mammary sentinel lymph node lymphatic drainage in breast cancer.Oncotarget · 2016Article
- Role of SPECT-CT in breast cancer sentinel node biopsy when internal mammary chain drainage is observed.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2016Article
- Internal mammary sentinel lymph node biopsy: abandon or persist?OncoTargets and therapy · 2016Article
- Internal Mammary Sentinel Lymph Node Biopsy With Modified Injection Technique: High Visualization Rate and Accurate Staging.Medicine · 2015Article
- The Role of the Plastic Surgeon in Sentinel Lymph Node Biopsy of Internal Mammary Nodes.Archives of plastic surgery · 2015Article
- Validation study of the modified injection technique for internal mammary sentinel lymph node biopsy in breast cancer.OncoTargets and therapy · 2015Article
- Main controversies in breast cancer.World journal of clinical oncology · 2014Review
- Internal Mammary Sentinel Node Biopsy in Breast Cancer. Is it Indicated?Pathology oncology research : POR · 2014Article
- Radiation dose to the nodal regions during prone versus supine breast irradiation.Therapeutics and clinical risk management · 2014Article
- Why do we need irradiation of internal mammary lymph nodes in patients with breast cancer: Analysis of lymph flow and radiotherapy studies.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Routine removal of the internal mammary chain (IMC) sentinel node in breast cancer patients remains a subject of discussion. The aim of this study was to determine the impact of routinely performed IMC sentinel node biopsy on the systemic and locoregional treatments plan. All patients with biopsy proven breast cancer who underwent a sentinel node procedure between 2002 and 2011 were included in a prospective database. In cases of IMC drainage, successful exploration of the IMC (i.e., sentinel node removed) and surgical complications were registered. If the removed sentinel node contained malignant cells we determined if this altered the treatment plan when practising the current guidelines. In total, 119 of the 493 included patients showed IMC drainage on lymphoscintigraphy. Exploration of the IMC was performed in 107 (89 %) patients; in 86/107 (80 %) exploration was successful. In 14/107 patients (13 %) the IMC sentinel node was tumor positive. Macro and micro metastases were found in eight and six patients, respectively. In the group of patients who underwent surgical exploration of the IMC, systemic treatment was changed in none, radiotherapy treatment in 13/107 patients (11 %). Routine sentinel node biopsy of the IMC does not alter the systemic treatment. Radiotherapy treatment is altered in a small proportion of the patients; however, solid scientific evidence for this adjustment is lacking.
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