Trial reportEuropean journal of applied physiology2013
Effect of time of day and partial sleep deprivation on plasma concentrations of IL-6 during a short-term maximal performance.
Trial report in European journal of applied physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Sleep Deprivation, Cytokine Dysregulation, and the Risk of Cardiac Arrhythmia in Dogs.Veterinary medicine and science · 2026Pooled it
- Effects of Experimental Sleep Deprivation on Peripheral Inflammation: An Updated Meta-Analysis of Human Studies.Journal of sleep research · 2026Pooled it
- Effects of sleep deprivation on sports performance and perceived exertion in athletes and non-athletes: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Diurnal variation in variables related to cognitive performance: a systematic review.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Effects of Acute Sleep Loss on Physical Performance: A Systematic and Meta-Analytical Review.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation.Biological psychiatry · 2016Pooled it
- Pooled it
- Relationship between Duration of Sleep and Hypertension in Adults: A Meta-Analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2015Pooled it
- Trial
- Trait positive affect buffers the association between experimental sleep disruption and inflammation.Psychoneuroendocrinology · 2021Trial
- Continuous theta burst stimulation improves sleep quality and thereby enhances athletic performance in athletes with sleep disorders: A randomized controlled trial.Journal of exercise science and fitness · 2026Article
- Exercise-modulated IL-6 in cancer cachexia: molecular mechanisms and therapeutic potential.Journal of translational medicine · 2026Review
- The Acute Effects of 25- Versus 60-Minute Naps on Agility and Vertical Jump Performance in Elite Youth Soccer Players: The Role of Individual Chronotype.Life (Basel, Switzerland) · 2025Article
- Article
- Current Aspects of Selected Factors to Modulate Brain Health and Sports Performance in Athletes.Nutrients · 2024Review
- Effects of Acute Sleep Deprivation on Sporting Performance in Athletes: A Comprehensive Systematic Review and Meta-Analysis.Nature and science of sleep · 2024Review
- The association between sleep duration and myopia among Chinese school-age students: mediation effect of physical activity.Frontiers in public health · 2024Article
- Sleep disruption induces activation of inflammation and heightens risk for infectious disease: Role of impairments in thermoregulation and elevated ambient temperature.Temperature (Austin, Tex.) · 2023Article
- Article
- Physical activity as a promising alternative for young people with juvenile idiopathic arthritis: Towards an evidence-based prescription.Frontiers in immunology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was designed to evaluate the effect of time of day and partial sleep deprivation (PSD) on short-term maximal performance and level of interleukin-6 (IL-6) in trained subjects. In a randomized order, 12 football players were asked to perform a 30-s Wingate test during which we measured the peak (PP) and mean (MP) powers. Measurements were performed at 0800 and 1800 hours, after two nocturnal regimens: (1) a reference normal sleep night (RN) and (2) 4 h of PSD caused by an early awakening. Plasma IL-6 concentrations were measured before (P1), immediately after (P2), and 60 min after the exercise (P3). PP and MP improved significantly from the morning to the afternoon after RN (P < 0.05) and from the afternoon to the morning after PSD (P < 0.05). Compared to RN, PP and MP were not affected by PSD the following morning. However, there was a significant decrease in PP and MP (P < 0.001) after the PSD at 1800 hours. In all conditions, IL-6 and resting core temperature were significantly higher (P < 0.05) in the afternoon than in the morning. In all sessions, IL-6 levels increased significantly from P1 to P2 (P < 0.01) and remained elevated in the afternoon during the recovery period after PSD (P < 0.05). However, no significant difference was observed in IL-6 between P1 and P3 during RN and PSD at 0800 hours. In conclusion, a short-term high-intensity exercise may increase the IL-6 concentrations in the morning and the afternoon. Moreover, IL-6 remained elevated during the recovery period in the afternoon after the PSD at the end of the night.
Indexed as
Identifiers
22677919What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.