Evidence map›Paper›PMID 22677184›Full record

ReviewTrends in immunology2012

Early events regulating immunity and pathogenesis during Listeria monocytogenes infection.

Matthew A Williams, Rebecca L Schmidt, Laurel L Lenz

Abstract readReview
In one paragraph

Review in Trends in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Innate and Adaptive Immune Responses duringMicrobiology spectrum · 2019
    Article
  14. Article
  15. Article
  16. MicroRNA-21 Limits Uptake ofFrontiers in cellular and infection microbiology · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. The Listeria monocytogenes strain 10403S BioCyc database.Database : the journal of biological databases and curation · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Matthew A WilliamsDepartment of Pathology, University of Utah, 15 North Medical Drive East, Salt Lake City, UT 84112, USA.
Rebecca L Schmidt
Laurel L Lenz
University of Colorado Denver · USUniversity of Utah · US

Funding

Molecular Mechanisms of Immune ToleranceT32AI074491 · NIAID · NATIONAL JEWISH HEALTH · PI CAMBIER, JOHN C, PELANDA, ROBERTA · 2009 to 2023
$4.1M
Immune Modulation by Bacterial AutolysinsR01AI065638 · NIAID · UNIVERSITY OF COLORADO DENVER · PI LENZ, LAUREL L · 2006 to 2016
$3.8M
The role of antigenic stimulatory strength in the selection and differentiation oR01AI080830 · NIAID · UNIVERSITY OF UTAH · PI WILLIAMS, MATTHEW A · 2010 to 2014
$1.8M
Active Subversion of Innate Immunity by Bacterial LysM ProteinR56AI065638 · NIAID · NATIONAL JEWISH HEALTH · PI LENZ, LAUREL L · 2011 to 2011
$396k
NIAID NIH HHS R01 AI065638NIAID NIH HHS R01 AI080830NIAID NIH HHS R56 AI065638
6 · The paper itself

Abstract

Listeria monocytogenes (Lm) is both a life-threatening pathogen of humans and a model organism that is widely used to dissect the mechanisms of innate and adaptive immune resistance to infection. Specific aspects of the immune response to systemic Lm infection can be protective, neutral, or in some cases deleterious. In this review, we seek to provide an overview of the early events during Lm infection that dictate or regulate host innate and adaptive immune responses. We highlight several recent developments that add to our understanding of the complex interplay between inflammatory responses, host susceptibility to infection, and the development of protective immunity.

Indexed as

Adaptive ImmunityAnimalsDendritic CellsHumansImmunity, InnateKiller Cells, NaturalListeria monocytogenesListeriosis

Identifiers

PMID22677184
PMCPMC3440530
OpenAlexW2051551967

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.