ReviewCurrent opinion in chemical biology2012
Synthetic in vitro circuits.
Review in Current opinion in chemical biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Lipid vesicle-based molecular robots.Lab on a chip · 2024Review
- Evolution and synthetic biology.Current opinion in microbiology · 2023Review
- Programmable Biomolecule-Mediated Processors.Journal of the American Chemical Society · 2023Review
- Review
- Rapid and Scalable Characterization of CRISPR Technologies Using an E. coli Cell-Free Transcription-Translation System.Molecular cell · 2018Article
- Cell-free TXTL synthesis of infectious bacteriophage T4 in a single test tube reaction.Synthetic biology (Oxford, England) · 2018Article
- Artificial cell mimics as simplified models for the study of cell biology.Experimental biology and medicine (Maywood, N.J.) · 2017Review
- Cell-free synthetic biology forBiochemical Society transactions · 2017Review
- Synthetic Gene Expression Circuits for Designing Precision Tools in Oncology.Frontiers in cell and developmental biology · 2017Review
- Supramolecular Control over Split-Luciferase Complementation.Angewandte Chemie (International ed. in English) · 2016Article
- Control theory meets synthetic biology.Journal of the Royal Society, Interface · 2016Review
- Review
- Design and application of cotranscriptional non-enzymatic RNA circuits and signal transducers.Nucleic acids research · 2014Article
- Building synthetic memory.Current biology : CB · 2013Review
- Ultrasensitivity by molecular titration in spatially propagating enzymatic reactions.Biophysical journal · 2013Article
- Scaling down DNA circuits with competitive neural networks.Journal of the Royal Society, Interface · 2013Article
- Cooperative working of bacterial chromosome replication proteins generated by a reconstituted protein expression system.Nucleic acids research · 2013Article
- Article
- A simplified and robust protocol for immunoglobulin expression in Escherichia coli cell-free protein synthesis systems.Biotechnology progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Inspired by advances in the ability to construct programmable circuits in living organisms, in vitro circuits are emerging as a viable platform for designing, understanding, and exploiting dynamic biochemical circuitry. In vitro systems allow researchers to directly access and manipulate biomolecular parts without the unwieldy complexity and intertwined dependencies that often exist in vivo. Experimental and computational foundations in DNA, DNA/RNA, and DNA/RNA/protein based circuitry have given rise to systems with more than 100 programmed molecular constituents. Functionally, they have diverse capabilities including: complex mathematical calculations, associative memory tasks, and sensing of small molecules. Progress in this field is showing that cell-free synthetic biology is a versatile testing ground for understanding native biological circuits and engineering novel functionality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.