Evidence map›Paper›PMID 22674485›Full record

ArticleDer Unfallchirurg2012

[Diagnosis and treatment of periprosthetic infections].

M Lenz, G O Hofmann, T Mückley

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Unfallchirurg, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. [Infected knee prostheses. Part 2: chronic late infections].Operative Orthopadie und Traumatologie · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

M LenzKlinik für Unfall-, Hand und Wiederherstellungschirurgie, Friedrich-Schiller-Universität, Erlanger Allee 101, 07747, Jena, Deutschland. mark.lenz@med.uni-jena.de
G O Hofmann
T Mückley
Friedrich Schiller University Jena · DEKlinikum Coburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The differentiation of periprosthetic infections into early onset and late onset infections is the determining factor fores the therapeutic strategy. The diagnosis of chronic unapparent infections is sometimes difficult. The therapeutic success, especially in early onset infections, is essentially influenced by a well-timed diagnosis and an immediate therapy. Surgical wound debridement with preservation of the prosthesis, one-stage replacement and two-stage replacement all with concomitant appropriate systemically administered double combined antibiotics are therapeutic options depending on factors, such as the duration of the infection. Prosthesis replacement is currently the only option to treat biofilm colonization of endoprosthetic surfaces. The bacterial adhesion on polyethylene can be extremely resistant. Due to the therapeutic consequences, periprosthetic infections remain one of the worst complications in endoprosthetic joint replacement.

Indexed as

Anti-Bacterial AgentsBacterial InfectionsCombined Modality TherapyDebridementDevice RemovalHumansJoint ProsthesisOsteotomyProsthesis-Related InfectionsReoperationAnti-Bacterial Agents

Identifiers

PMID22674485
OpenAlexW2165865515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.