ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Emergence of coordinated plasticity in the cochlear nucleus and cerebellum.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Synaptic input variation enhances rate coding at the expense of temporal precision in cochlear nucleus neurons.PLoS biology · 2026Article
- Ultrastructural changes at auditory nerve synapses following moderate noise exposure.bioRxiv : the preprint server for biology · 2025Article
- Convergence of Type 1 Spiral Ganglion Neuron Subtypes onto Principal Neurons of the Anteroventral Cochlear Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse.Frontiers in molecular neuroscience · 2024Article
- Induction of Activity-Dependent Plasticity at Auditory Nerve Synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Role of GluA3 AMPA Receptor Subunits in the Presynaptic and Postsynaptic Maturation of Synaptic Transmission and Plasticity of Endbulb-Bushy Cell Synapses in the Cochlear Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Effects of Non-traumatic Noise and Conductive Hearing Loss on Auditory System Function.Neuroscience · 2019Review
- Changes in Properties of Auditory Nerve Synapses following Conductive Hearing Loss.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Target-specific regulation of presynaptic release properties at auditory nerve terminals in the avian cochlear nucleus.Journal of neurophysiology · 2016Article
- Presynaptic Adenosine Receptor-Mediated Regulation of Diverse Thalamocortical Short-Term Plasticity in the Mouse Whisker Pathway.Frontiers in neural circuits · 2016Article
- Different pools of glutamate receptors mediate sensitivity to ambient glutamate in the cochlear nucleus.Journal of neurophysiology · 2015Article
- Skipped-stimulus approach reveals that short-term plasticity dominates synaptic strength during ongoing activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Activity-dependent, homeostatic regulation of neurotransmitter release from auditory nerve fibers.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Diverse thalamocortical short-term plasticity elicited by ongoing stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- How do short-term changes at synapses fine-tune information processing?The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Synapses formed by one cell type onto another cell type tend to show characteristic short-term plasticity, which varies from facilitating to depressing depending on the particular system. Within a population of synapses, plasticity can also be variable, and it is unknown how this plasticity is determined on a cell-by-cell level. We have investigated this in the mouse cochlear nucleus, where auditory nerve (AN) fibers contact bushy cells (BCs) at synapses called "endbulbs of Held." Synapses formed by different AN fibers onto one BC had plasticity that was more similar than would be expected at random. Experiments using MK-801 indicated that this resulted in part from similarity in the presynaptic probability of release. The similarity was not present in immature synapses but emerged after the onset of hearing. In addition, the phenomenon occurred at excitatory synapses in the cerebellum. This indicates that postsynaptic cells coordinate the plasticity of their inputs, which suggests that plasticity is of fundamental importance to synaptic function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.