ArticleCornea2012
Fungal keratitis responsive to moxifloxacin monotherapy.
Article in Cornea, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 18 citations in OpenAlex.
- A Convolutional Neural Network Using Anterior Segment Photos for Infectious Keratitis Identification.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- The Endophytic BacteriaJournal of microbiology and biotechnology · 2020Article
- Fungal keratitis: study of increasing trend and common determinants.Nepal journal of epidemiology · 2017Article
- The antibacterial agent, moxifloxacin inhibits virulence factors of Candida albicans through multitargeting.World journal of microbiology & biotechnology · 2017Article
- Antiviral, antifungal, and antiparasitic activities of fluoroquinolones optimized for treatment of bacterial infections: a puzzling paradox or a logical consequence of their mode of action?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purposeTo report 5 cases of culture-proven fungal keratitis that resolved with moxifloxacin monotherapy.
methodsCase reports and review of medical literature. Five patients with fungal keratitis were treated with topical moxifloxacin.
resultsAll 5 patients had resolution of their infection with topical moxifloxacin monotherapy.
conclusionsTopical fluoroquinolone agents may have significant antifungal properties. However, the vast majority of fungal keratitis patients cannot be cured with fluoroquinolone monotherapy. An initial response of keratitis to topical fluoroquinolone therapy should not lead to the assumption that the infection is bacterial because the possibility of fungal infection cannot be ruled out on that basis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.