Evidence map›Paper›PMID 22673088›Full record

ArticleThe Journal of veterinary medical science2012

Cell surface molecules involved in infection mediated by lymphocytic choriomeningitis virus glycoprotein.

Masayuki Shimojima, Yoshihiro Kawaoka

Open access · hybridAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Entry inhibitors as arenavirus antivirals.Frontiers in microbiology · 2024
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Pseudotyped Viruses for Mammarenavirus.Advances in experimental medicine and biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Masayuki ShimojimaDivision of Virology, Department of Microbiology and Immunology, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Yoshihiro Kawaoka
Japan Science and Technology Agency · JPThe University of Tokyo · JP

Funding

Molecular Pathogenesis of Lassa virus infectionR21AI055625 · NIAID · UNIVERSITY OF WISCONSIN MADISON · PI KAWAOKA, YOSHIHIRO · 2003 to 2004
$582k
NIAID NIH HHS R21 AI055625
6 · The paper itself

Abstract

The glycoprotein (GP) of lymphocytic choriomeningitis virus (LCMV), the prototype arenavirus, is a promising envelope protein of lentiviral pseudotype vectors for gene therapy. The distribution of dystroglycan, a known receptor for LCMV, cannot explain the narrow tropism of LCMV-GP-pseudotypes. Here, we examined whether infection of LCMV-GP-pseudotypes was affected by the expression of four cell surface molecules-Axl and Tyro3 (from the TAM family) and DC-SIGN and LSECtin (from the C-type lectin family)-that are known receptors of Lassa virus, another arenavirus. All four molecules enhanced LCMV-GP-pseudotype infection of cells. These results help explain the tropism of LCMV-GP-pseudotypes and further our understanding of LCMV infection in animals.

Indexed as

Arenaviridae InfectionsCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinGenetic TherapyGenetic VectorsGlycoproteinsHumansJurkat CellsLectins, C-TypeLymphocytic choriomeningitis virusReceptor Protein-Tyrosine KinasesReceptors, Cell SurfaceReceptors, VirusCell Adhesion MoleculesCLEC4G protein, humanDC-Specific ICAM-3 Grabbing NonintegrinGlycoproteinsLectins, C-TypeReceptor Protein-Tyrosine KinasesReceptors, Cell SurfaceReceptors, VirusTYRO3 protein, human

Identifiers

PMID22673088
PMCPMC6133296
OpenAlexW2054945063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.