Evidence map›Paper›PMID 22672914›Full record

ArticleJournal of epidemiology2012

BMI is strongly associated with hypertension, and waist circumference is strongly associated with type 2 diabetes and dyslipidemia, in northern Chinese adults.

Ren-Nan Feng, Chen Zhao, Cheng Wang, Yu-Cun Niu, Kang Li, Fu-Chuan Guo, Song-Tao Li, Chang-Hao Sun, Ying Li

Open access · goldAbstract read
In one paragraph

Article in Journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 175 citations in OpenAlex.

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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Ren-Nan FengDepartment of Nutrition and Food Hygiene, School of Public Health, Harbin Medical University, P R China.
Chen Zhao
Cheng Wang
Yu-Cun Niu
Kang Li
Fu-Chuan Guo
Song-Tao Li
Chang-Hao Sun
Ying Li
Harbin Medical University · CN

Funding

Alcohol-induced plasticity within CRF2 microcircuits in distinct amygdala nucleiR00AA023002 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HERMAN, MELISSA A · 2017 to 2019
$732k
Alcohol-induced plasticity within CRF2 microcircuits in distinct amygdala nucleiK99AA023002 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HERMAN, MELISSA A · 2015 to 2016
$284k
NIAAA NIH HHS K99 AA023002NIAAA NIH HHS R00 AA023002
6 · The paper itself

Abstract

backgroundObesity is closely associated with chronic diseases such as hypertension, type 2 diabetes mellitus (T2DM), and dyslipidemia. We analyzed the optimal obesity index cut-off values for metabolic syndrome (MetS), and identified the obesity index that is more closely associated with these chronic diseases, in a population of northern Chinese.

methodsWe surveyed 8940 adults (age, 20-74 years) living in northern China for chronic diseases. Receiver operating characteristics (ROC) analysis, relative risk, and multivariate regression were used to develop an appropriate index and optimal cut-off values for MetS and obesity-related chronic diseases.

resultsWaist circumference (WC) and body mass index (BMI) were good markers for MetS, WC was a good marker for T2DM and dyslipidemia, and BMI was a good marker for hypertension. The optimal BMI cut-off value of MetS was 24 kg/m², and the optimal WC cut-offs were 86 cm and 78 cm in men and women, respectively. Relative risk regression models showed that BMI was associated with hypertension, T2DM, and hypertriglyceridemia and a higher prevalence ratio (PR) for hypertension: 2.35 (95% CI, 2.18-2.50). WC was associated with T2DM, hypertension, and hypertriglyceridemia, with PRs of 2.05 (1.63-2.55) for T2DM and 2.47 (2.04-2.85) for hypertriglyceridemia. In multivariate regression models, the standardized regression coefficients (SRCs) of BMI were greater for SBP and DBP, and the SRC of WC was greater for fasting blood glucose, 2-hour postload blood glucose, triglyceride, and total cholesterol.

conclusionsOur analysis of a population of northern Chinese indicates that the optimal cut-off values for MetS are WCs of 86 cm in men and 78 cm in women and a BMI of 24 kg/m² in both sexes. BMI was strongly associated with hypertension, while WC was strongly associated with T2DM and dyslipidemia.

Indexed as

Body Mass IndexWaist CircumferenceAdultAgedAnthropometryChinaDiabetes Mellitus, Type 2DyslipidemiasFemaleHumansHypertensionMaleMetabolic SyndromeMiddle AgedMultivariate AnalysisObesity

Identifiers

PMID22672914
PMCPMC3798650
OpenAlexW2030353283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.