Trial reportBMC psychiatry2012
The Depression in Visual Impairment Trial (DEPVIT): trial design and protocol.
Trial report in BMC psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Low vision rehabilitation for better quality of life in visually impaired adults.The Cochrane database of systematic reviews · 2020Pooled it
- Depressive symptoms in people with vision impairment: a cross-sectional study to identify who is most at risk.BMJ open · 2019Trial
- Trial
- Stepped-care to prevent depression and anxiety in visually impaired older adults--design of a randomised controlled trial.BMC psychiatry · 2013Trial
- Association of Visual Health With Depressive Symptoms and Brain Imaging Phenotypes Among Middle-Aged and Older Adults.JAMA network open · 2022Article
- Vision-Related Quality of Life After Vitrectomy: Cross-Sectional Study from Jordan.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- How do community-based eye care practitioners approach depression in patients with low vision? A mixed methods study.BMC psychiatry · 2019Article
- Visual impairment and risk of depression: A longitudinal follow-up study using a national sample cohort.Scientific reports · 2018Article
- Anxiety and depression in patients with advanced macular degeneration: current perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2016Review
- Longitudinal observation, evaluation and interpretation of coping with mental (emotional) health in low vision rehabilitation using the Dutch ICF Activity Inventory.Health and quality of life outcomes · 2014Observational
- Visual impairment is associated with physical and mental comorbidities in older adults: a cross-sectional study.BMC medicine · 2014Article
- Depressive symptoms among the visually disabled in Wuhan: an epidemiological survey.Shanghai archives of psychiatry · 2013Article
- Update on depression and age-related macular degeneration.Current opinion in ophthalmology · 2013Review
- Modifying Cognitive-Behavioral Therapy for a Depressed Older Adult With Partial Sight: A Case Report.Gerontology & geriatric medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of depression in people with a visual disability is high but screening for depression and referral for treatment is not yet an integral part of visual rehabilitation service provision. One reason for this may be that there is no good evidence about the effectiveness of treatments in this patient group. This study is the first to evaluate the effect of depression treatments on people with a visual impairment and co morbid depression. METHODS /
designThe study is an exploratory, multicentre, individually randomised waiting list controlled trial. Participants will be randomised to receive Problem Solving Therapy (PST), a 'referral to the GP' requesting treatment according to the NICE's 'stepped care' recommendations or the waiting list arm of the trial. The primary outcome measure is change (from randomisation) in depressive symptoms as measured by the Beck's Depression Inventory (BDI-II) at 6 months. Secondary outcomes include change in depressive symptoms at 3 months, change in visual function as measured with the near vision subscale of the VFQ-48 and 7 item NEI-VFQ at 3 and 6 months, change in generic health related quality of life (EQ5D), the costs associated with PST, estimates of incremental cost effectiveness, and recruitment rate estimation. DISCUSSION: Depression is prevalent in people with disabling visual impairment. This exploratory study will establish depression screening and referral for treatment in visual rehabilitation clinics in the UK. It will be the first to explore the efficacy of PST and the effectiveness of NICE's 'stepped care' approach to the treatment of depression in people with a visual impairment.
trial registrationISRCTN46824140.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.