ArticleBMC genomics2012
A high-resolution map of the Nile tilapia genome: a resource for studying cichlids and other percomorphs.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- Genome-wide association analysis of adaptation to oxygen stress in Nile tilapia (Oreochromis niloticus).BMC genomics · 2021Pooled it
- Article
- A chromosome-anchored reference assembly for the gray snapper, Lutjanus griseus.Molecular biology reports · 2025Article
- Assessment of biochemical biomarkers and environmental stress indicators in some freshwater fish.Environmental geochemistry and health · 2024Article
- A comparative study on the tolerance of tilapia (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- High cholesterol intake remodels cholesterol turnover and energy homeostasis in Nile tilapia (Marine life science & technology · 2023Article
- Mapping of quantitative trait loci underlying a magic trait in ongoing ecological speciation.BMC genomics · 2021Article
- Exploring the Multimodal Role ofAnimals : an open access journal from MDPI · 2021Article
- Impaired peroxisomal fat oxidation induces hepatic lipid accumulation and oxidative damage in Nile tilapia.Fish physiology and biochemistry · 2020Article
- Article
- Transcriptome Profiling and Analysis of Genes Associated with High Temperature-Induced Masculinization in Sex-Undifferentiated Nile Tilapia Gonad.Marine biotechnology (New York, N.Y.) · 2020Article
- Genetic architecture of a key reproductive isolation trait differs between sympatric and non-sympatric sister species of Lake Victoria cichlids.Proceedings. Biological sciences · 2020Article
- Identification and Characterization of a Non-muscular Myostatin in the Nile Tilapia.Frontiers in endocrinology · 2020Article
- A Molecular Cytogenetic Map of Scallop (Patinopecten yessoensis).Marine biotechnology (New York, N.Y.) · 2019Article
- Genetic diversity of Nile tilapia (Oreochromis niloticus) throughout West Africa.Scientific reports · 2019Article
- Chromosome-scale assemblies reveal the structural evolution of African cichlid genomes.GigaScience · 2019Article
- Constructing a High-Density Genetic Linkage Map for Large Yellow Croaker (Larimichthys crocea) and Mapping Resistance Trait Against Ciliate Parasite Cryptocaryon irritans.Marine biotechnology (New York, N.Y.) · 2019Article
- Article
- Effects of Lactogen 13, a New Probiotic Preparation, on Gut Microbiota and Endocrine Signals Controlling Growth and Appetite of Oreochromis niloticus Juveniles.Microbial ecology · 2018Article
- A Dense Linkage Map of Lake Victoria Cichlids Improved theG3 (Bethesda, Md.) · 2018Article
Corrections and comments
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Authors and funding
19 authors at 10 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Nile tilapia (Oreochromis niloticus) is the second most farmed fish species worldwide. It is also an important model for studies of fish physiology, particularly because of its broad tolerance to an array of environments. It is a good model to study evolutionary mechanisms in vertebrates, because of its close relationship to haplochromine cichlids, which have undergone rapid speciation in East Africa. The existing genomic resources for Nile tilapia include a genetic map, BAC end sequences and ESTs, but comparative genome analysis and maps of quantitative trait loci (QTL) are still limited.
resultsWe have constructed a high-resolution radiation hybrid (RH) panel for the Nile tilapia and genotyped 1358 markers consisting of 850 genes, 82 markers corresponding to BAC end sequences, 154 microsatellites and 272 single nucleotide polymorphisms (SNPs). From these, 1296 markers could be associated in 81 RH groups, while 62 were not linked. The total size of the RH map is 34,084 cR(3500) and 937,310 kb. It covers 88% of the entire genome with an estimated inter-marker distance of 742 Kb. Mapping of microsatellites enabled integration to the genetic map. We have merged LG8 and LG24 into a single linkage group, and confirmed that LG16-LG21 are also merged. The orientation and association of RH groups to each chromosome and LG was confirmed by chromosomal in situ hybridizations (FISH) of 55 BACs. Fifty RH groups were localized on the 22 chromosomes while 31 remained small orphan groups. Synteny relationships were determined between Nile tilapia, stickleback, medaka and pufferfish.
conclusionThe RH map and associated FISH map provide a valuable gene-ordered resource for gene mapping and QTL studies. All genetic linkage groups with their corresponding RH groups now have a corresponding chromosome which can be identified in the karyotype. Placement of conserved segments indicated that multiple inter-chromosomal rearrangements have occurred between Nile tilapia and the other model fishes. These maps represent a valuable resource for organizing the forthcoming genome sequence of Nile tilapia, and provide a foundation for evolutionary studies of East African cichlid fishes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.