Evidence map›Paper›PMID 22669628›Full record

ArticlemBio2012

Escherichia coli: great diversity around a common core.

Danilo G Moriel, Roberto Rosini, Kate L Seib, Laura Serino, Mariagrazia Pizza, Rino Rappuoli

Abstract read
In one paragraph

Article in mBio, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Emergence of Multidrug-ResistantAnimals : an open access journal from MDPI · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Characterization of blaBMC research notes · 2018
    Article
  14. Molecular Characterization of DiarrheagenicEuropean journal of microbiology & immunology · 2017
    Article
  15. Nod2: The intestinal gate keeper.PLoS pathogens · 2017
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danilo G MorielNovartis Vaccines and Diagnostics, Sienna, Italy.
Roberto Rosini
Kate L Seib
Laura Serino
Mariagrazia Pizza
Rino Rappuoli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledEscherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. coli genome sequences for the presence of nine previously identified protective extraintestinal pathogenic E. coli antigens suggested the feasibility of a combination vaccine as a universal intervention against all pathogenic E. coli strains. IMPORTANCE: This article reports on the feasibility of a combination vaccine as a universal intervention against all pathogenic Escherichia coli strains.

Indexed as

Disease OutbreaksGenetic VariationAntigens, BacterialConserved SequenceEscherichia coliEscherichia coli InfectionsEscherichia coli VaccinesGenome, BacterialGermanyHumansAntigens, BacterialEscherichia coli Vaccines

Identifiers

PMID22669628
PMCPMC3374390

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.