ReviewPaediatrics and international child health2012
Controversies in dengue pathogenesis.
Review in Paediatrics and international child health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- Comparing the usefulness of the 1997 and 2009 WHO dengue case classification: a systematic literature review.The American journal of tropical medicine and hygiene · 2014Pooled it
- Enhancing epitope of PEDV spike protein.Frontiers in microbiology · 2022Article
- Dengue Infection - Recent Advances in Disease Pathogenesis in the Era of COVID-19.Frontiers in immunology · 2022Review
- Prevalence of arbovirus antibodies in young healthy adult population in Brazil.Parasites & vectors · 2021Article
- Current Understanding of the Pathogenesis of Dengue Virus Infection.Current microbiology · 2021Review
- Refining Clinical Triage and Management of Dengue Infection in Children: A Timely Approach.Indian pediatrics · 2020Article
- Nutritional status impacts dengue virus infection in mice.BMC biology · 2020Article
- Severe dengue categories as research endpoints-Results from a prospective observational study in hospitalised dengue patients.PLoS neglected tropical diseases · 2020Observational
- Clinical profile and atypical manifestation ofJournal of family medicine and primary care · 2020Article
- Review
- Clinical profile and predictors of Severe Dengue disease: A study from South India.Caspian journal of internal medicine · 2018Article
- Elimination of Falciparum Malaria and Emergence of Severe Dengue: An Independent or Interdependent Phenomenon?Frontiers in microbiology · 2018Article
- IL-10 and socs3 Are Predictive Biomarkers of Dengue Hemorrhagic Fever.Mediators of inflammation · 2017Article
- Article
- The Golgi associated ERI3 is a Flavivirus host factor.Scientific reports · 2016Article
- Serum Procalcitonin and Peripheral Venous Lactate for Predicting Dengue Shock and/or Organ Failure: A Prospective Observational Study.PLoS neglected tropical diseases · 2016Observational
- Article
- Development and utility of an in vitro, fluorescence-based assay for the discovery of novel compounds against dengue 2 viral protease.Tropical medicine and health · 2016Article
- Vitamin D-Regulated MicroRNAs: Are They Protective Factors against Dengue Virus Infection?Advances in virology · 2016Review
- New insights into the immunopathology and control of dengue virus infection.Nature reviews. Immunology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research into the pathogenesis of dengue fever has exploded over the last half-century, with issues that were considered simple becoming more complex as additional data are found. This has led to the development of a number of controversies that are being studied across the globe and debated in the literature. In this paper, the following six controversies are analysed and, where possible, resolved: the 1997 World Health Organization (WHO) case definition of dengue haemorrhagic fever (DHF) is not useful; DHF is not significantly associated with secondary dengue infection; DHF results from infection with a 'virulent' dengue virus; DHF is owing to abnormal T-cell responses; DHF results from auto-immune responses; and DHF results from direct infection of endothelial cells.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.