ArticleJournal of applied oral science : revista FOB
Alveolar bone healing process in spontaneously hypertensive rats (SHR). A radiographic densitometry study.
Article in Journal of applied oral science : revista FOB. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 38 citations in OpenAlex.
- Evaluation of Patients Perspectives on Dental Implants and Bone Graft Surgery.Journal of pharmacy & bioallied sciences · 2025Article
- Nanoarchitectonics for Advancing Bone Graft Technology: Integration of Silver Nanoparticles Against Bacteria and Fungi.Microorganisms · 2024Article
- Advances in Regenerative and Reconstructive Medicine in the Prevention and Treatment of Bone Infections.Biology · 2024Review
- Article
- Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease.Frontiers in pharmacology · 2020Article
- Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats.Journal of applied oral science : revista FOB · 2019Article
- Alveolar bone healing in rats: micro-CT, immunohistochemical and molecular analysis.Journal of applied oral science : revista FOB · 2018Article
- A Comparison of Radiographic Film Densitometry Using a New Computerized Tool with a Digital Densitometer.Journal of dentistry (Tehran, Iran) · 2016Article
- Bone grafts utilized in dentistry: an analysis of patients' preferences.BMC medical ethics · 2015Article
- Hypertension modifies OPG, RANK, and RANKL expression during the dental socket bone healing process in spontaneously hypertensive rats.Clinical oral investigations · 2015Article
- Impact of ellagic acid in bone formation after tooth extraction: an experimental study on diabetic rats.TheScientificWorldJournal · 2014Article
- Factors affecting the periapical healing process of endodontically treated teeth.Journal of applied oral science : revista FOBReview
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledHypertension is one of the most important public health problems worldwide. If undiagnosed or untreated, this pathology represents a systemic risk factor and offers unfavorable conditions for dental treatments, especially those requiring bone healing.
objectivesThe purpose of this study was to demonstrate, by analysis of bone mineral density (BMD), that the alveolar bone healing process is altered in spontaneously hypertensive rats (SHRs). MATERIAL AND
methodsWistar rats and SHRs were submitted to extraction of the upper right incisor and were euthanized 7, 14, 21, 28 and 42 days after surgery. Right maxillae were collected, radiographed and analyzed using Digora software. BMD was expressed as minimum (min), middle (med) and maximum (max) in the medium (MT) and apical (AT) thirds of the dental alveolus.
resultsThe results were compared across days and groups. Wistar showed difference in med and max BMD in the MT between 7 and 28 and also between 14 and 28 days. The AT exhibited significant difference in med and min BMD between 7 and 28 days, as well as difference in min BMD between 28 and 42 days. SHRs showed lower med BMD in the MT at 28 days when compared to 21 and 42 days. Differences were observed across groups in med and min BMD at day 28 in the MT and AT; and in max BMD at 14, 21 and 42 days in the MT.
conclusionsThese results suggest that the alveolar bone healing process is delayed in SHRs comparing with Wistar rats.
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