ArticleClinics (Sao Paulo, Brazil)2012
Metabolic assessment of elderly men with urolithiasis.
Article in Clinics (Sao Paulo, Brazil), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01246531 (Clinical Investigation of Aging Men With Renal Stones), which is not on this map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Investigation of Aging Men With Renal Stones: The Role of Bone Demineralization (Metabolic and Hormonal Assessment)
Who cites it
4 citing papers in PubMed, 13 citations in OpenAlex.
- Relationship Between Urolithiasis and Fatty Liver Disease: Findings in Computed Tomography.Tomography (Ann Arbor, Mich.) · 2020Article
- Article
- An update on metabolic assessment in patients with urinary lithiasis.World journal of urology · 2015Article
- A large series of extracorporeal shockwave lithotripsy in the very elderly.Therapeutic advances in urologyArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the presence of metabolic disorders in elderly men with urolithiasis.
methodsWe performed a case-control study. The inclusion criteria were as follows: (1) men older than 60 years of age and either (2) antecedent renal colic or an incidental diagnosis of urinary lithiasis after age 60 (case arm) or (3) no antecedent renal colic or incidental diagnosis of urolithiasis (control arm). Each individual underwent an interview, and those who were selected underwent all clinical protocol examinations: serum levels of total and ionized calcium, uric acid, phosphorus, glucose, urea, creatinine and parathyroid hormone, urine culture, and analysis of 24-hour urine samples (levels of calcium, citrate, creatinine, uric acid and sodium, pH and urine volume). Each case arm patient underwent two complete metabolic urinary investigations, whereas each control arm individual underwent one examination. ClinicalTrials.gov: NCT01246531.
resultsA total of 51 subjects completed the clinical investigation: 25 in the case arm and 26 in the control arm. In total, 56% of the case arm patients had hypocitraturia (vs. 15.4% in the control arm; p = 0.002). Hypernatriuria was detected in 64% of the case arm patients and in 30.8% of the controls (p = 0.017).
conclusionHypocitraturia and hypernatriuria are the main metabolic disorders in elderly men with urolithiasis.
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