ReviewOxidative medicine and cellular longevity2012
Anticancer activity of green tea polyphenols in prostate gland.
Review in Oxidative medicine and cellular longevity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 66 citations in OpenAlex.
- Dietary phenolic compounds as promising therapeutic agents for diabetes and its complications: A comprehensive review.Food science & nutrition · 2024Review
- Tea andChinese herbal medicines · 2022Article
- Polyvinyl Alcohol/Sodium Alginate Hydrogels Incorporated with Silver Nanoclusters via Green Tea Extract for Antibacterial Applications.Designed monomers and polymers · 2020Article
- Molecular Mechanisms and Bioavailability of Polyphenols in Prostate Cancer.International journal of molecular sciences · 2019Review
- Anti-Cancer Effects of Green Tea Polyphenols Against Prostate Cancer.Molecules (Basel, Switzerland) · 2019Review
- A Potential Role for Green Tea as a Radiation Sensitizer for Prostate Cancer.Pathology oncology research : POR · 2019Article
- Dietary polyphenols influence antimetabolite agents: methotrexate, 6-mercaptopurine and 5-fluorouracil in leukemia cell lines.Oncotarget · 2017Article
- Green Tea Catechins for Prostate Cancer Prevention: Present Achievements and Future Challenges.Antioxidants (Basel, Switzerland) · 2017Review
- Breast cancer chemopreventive and chemotherapeutic effects of Camellia Sinensis (green tea): an updated review.Electronic physician · 2017Review
- An overview on the role of dietary phenolics for the treatment of cancers.Nutrition journal · 2016Review
- ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases.Oxidative medicine and cellular longevity · 2016Review
- Dietary Antioxidant and Flavonoid Intakes Are Reduced in the Elderly.Oxidative medicine and cellular longevity · 2015Article
- Roles of autophagy induced by natural compounds in prostate cancer.BioMed research international · 2015Review
- Resources and biological activities of natural polyphenols.Nutrients · 2014Review
- Dietary agents and phytochemicals in the prevention and treatment of experimental ulcerative colitis.Journal of traditional and complementary medicine · 2014Review
- Induction of reactive oxygen species generation inhibits epithelial-mesenchymal transition and promotes growth arrest in prostate cancer cells.Molecular carcinogenesis · 2014Article
- Dietary antiaging phytochemicals and mechanisms associated with prolonged survival.The Journal of nutritional biochemistry · 2014Review
- Effects of honey and its mechanisms of action on the development and progression of cancer.Molecules (Basel, Switzerland) · 2014Review
- Pterostilbene-induced tumor cytotoxicity: a lysosomal membrane permeabilization-dependent mechanism.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 7 institutions in 3 countries.
Funding
Abstract
Numerous evidences from prevention studies in humans, support the existence of an association between green tea polyphenols consumption and a reduced cancer risk. Prostate cancer is one of the most frequently diagnosed male neoplasia in the Western countries, which is in agreement with this gland being particularly vulnerable to oxidative stress processes, often associated with tumorigenesis. Tea polyphenols have been extensively studied in cell culture and animal models where they inhibited tumor onset and progression. Prostate cancer appears a suitable target for primary prevention care, since it grows slowly, before symptoms arise, thus offering a relatively long time period for therapeutic interventions. It is, in fact, usually diagnosed in men 50-year-old or older, when even a modest delay in progression of the disease could significantly improve the patients quality of life. Although epidemiological studies have not yet yielded conclusive results on the chemopreventive and anticancer effect of tea polyphenols, there is an increasing trend to employ these substances as conservative management for patients diagnosed with less advanced prostate cancer. Here, we intend to review the most recent observations relating tea polyphenols to human prostate cancer risk, in an attempt to outline better their potential employment for preventing prostate cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.