ArticlePloS one2012
Evolution and association analysis of Ghd7 in rice.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Ghd7‑triggered transcriptional regulation for synergistically improving rice eating quality and yield.Nature communications · 2026Article
- Engineering non-coding DNA Elements in Rice: an Elegant Approach To fine-tune Agronomical Advantageous Traits.Rice (New York, N.Y.) · 2025Review
- Antagonistic Ghd7-OsNAC42 Complexes Modulate Carbon and Nitrogen Metabolism to Achieves Superior Quality and High Yield in Rice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Genetic Foundation of Leaf Senescence: Insights from Natural and Cultivated Plant Diversity.Plants (Basel, Switzerland) · 2024Review
- OsIAA23 Promotes Heading by Directly Downregulating Ghd7 in rice.Rice (New York, N.Y.) · 2024Article
- OsCKq1 Regulates Heading Date and Grain Weight in Rice in Response to Day Length.Rice (New York, N.Y.) · 2024Article
- Genome-wide association analysis identifies natural allelic variants associated with panicle architecture variation in African rice, Oryza glaberrima Steud.G3 (Bethesda, Md.) · 2023Article
- Reloading DNA History in Rice Domestication.Plant & cell physiology · 2022Review
- Mapping and Validation ofPlants (Basel, Switzerland) · 2022Article
- Major niche transitions in Pooideae correlate with variation in photoperiodic flowering and evolution of CCT domain genes.Journal of experimental botany · 2022Article
- Genome-wide association studies: assessing trait characteristics in model and crop plants.Cellular and molecular life sciences : CMLS · 2021Review
- Validating a segment on chromosome 7 of japonica for establishing low-cadmium accumulating indica rice variety.Scientific reports · 2021Article
- TargetingFrontiers in plant science · 2021Review
- Knockouts of a late flowering gene via CRISPR-Cas9 confer early maturity in rice at multiple field locations.Plant molecular biology · 2020Article
- Genetic effect of a new allele for the flowering time locusBreeding science · 2020Article
- Using Heading date 1 preponderant alleles from indica cultivars to breed high-yield, high-quality japonica rice varieties for cultivation in south China.Plant biotechnology journal · 2020Article
- Allelic Differentiation at thePlants (Basel, Switzerland) · 2019Article
- Uncovering of natural allelic variants of key yield contributing genes by targeted resequencing in rice (Oryza sativa L.).Scientific reports · 2019Article
- Role of genetic introgression during the evolution of cultivated rice (Oryza sativa L.).BMC evolutionary biology · 2018Article
- Genetic dissection and validation of candidate genes for flag leaf size in rice (Oryza sativa L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant height, heading date, and yield are the main targets for rice genetic improvement. Ghd7 is a pleiotropic gene that controls the aforementioned traits simultaneously. In this study, a rice germplasm collection of 104 accessions (Oryza sativa) and 3 wild rice varieties (O.rufipogon) was used to analyze the evolution and association of Ghd7 with plant height, heading date, and yield. Among the 104 accessions, 76 single nucleotide polymorphisms (SNPs) and six insertions and deletions were found within a 3932-bp DNA fragment of Ghd7. A higher pairwise π and θ in the promoter indicated a highly diversified promoter of Ghd7. Sixteen haplotypes and 8 types of Ghd7 protein were detected. SNP changes between haplotypes indicated that Ghd7 evolved from two distinct ancestral gene pools, and independent domestication processes were detected in indica and japonica varietals respectively. In addition to the previously reported premature stop mutation in the first exon of Ghd7, which caused phenotypic changes of multiple traits, we found another functional C/T mutation (SNP S_555) by structure-based association analysis. SNP S_555 is located in the promoter and was related to plant height probably by altering gene expression. Moreover, another seven SNP mutations in complete linkage were found to be associated with the number of spikelets per panicle, regardless of the photoperiod. These associations provide the potential for flexibility of Ghd7 application in rice breeding programs.
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