Evidence map›Paper›PMID 22665720›Full record

ArticleIEEE transactions on pattern analysis and machine intelligence2013

A sparse structure learning algorithm for Gaussian Bayesian Network identification from high-dimensional data.

Shuai Huang, Jing Li, Jieping Ye, Adam Fleisher, Kewei Chen, Teresa Wu, Eric Reiman, Alzheimer’s Disease Neuroimaging Initiative

Abstract read
In one paragraph

Article in IEEE transactions on pattern analysis and machine intelligence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Learning Discriminative Bayesian Networks from High-Dimensional Continuous Neuroimaging Data.IEEE transactions on pattern analysis and machine intelligence · 2016
    Article
  4. Review
  5. Article
  6. Discriminative Brain Effective Connectivity Analysis for Alzheimer's Disease: A Kernel Learning Approach upon Sparse Gaussian Bayesian Network.Conference on Computer Vision and Pattern Recognition Workshops. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. Workshops · 2013
    Article
  7. Article
  8. A Transfer Learning Approach for Predictive Modeling of Degenerate Biological Systems.Technometrics : a journal of statistics for the physical, chemical, and engineering sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuai HuangSchool of Computing, Informatics, and Decision Systems Engineering, Arizona State University, PO Box 878809, Tempe, AZ 85287-8809, USA.
Jing Li
Jieping Ye
Adam Fleisher
Kewei Chen
Teresa Wu
Eric Reiman
Alzheimer’s Disease Neuroimaging Initiative

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Sparse Structure Identification from High-Dimensional Epigenomic DataR01GM096194 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZHU, JI · 2010 to 2013
$1.0M
NIA NIH HHS U01 AG024904NIA NIH HHS U01AG024904NIGMS NIH HHS R01 GM096194PHS HHS 1R0IGM096194-01
6 · The paper itself

Abstract

Structure learning of Bayesian Networks (BNs) is an important topic in machine learning. Driven by modern applications in genetics and brain sciences, accurate and efficient learning of large-scale BN structures from high-dimensional data becomes a challenging problem. To tackle this challenge, we propose a Sparse Bayesian Network (SBN) structure learning algorithm that employs a novel formulation involving one L1-norm penalty term to impose sparsity and another penalty term to ensure that the learned BN is a Directed Acyclic Graph--a required property of BNs. Through both theoretical analysis and extensive experiments on 11 moderate and large benchmark networks with various sample sizes, we show that SBN leads to improved learning accuracy, scalability, and efficiency as compared with 10 existing popular BN learning algorithms. We apply SBN to a real-world application of brain connectivity modeling for Alzheimer's disease (AD) and reveal findings that could lead to advancements in AD research.

Indexed as

AlgorithmsNormal DistributionAlzheimer DiseaseArtificial IntelligenceBayes TheoremBrainGene Expression ProfilingHumans

Identifiers

PMID22665720
PMCPMC3924722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.