Evidence map›Paper›PMID 22665604›Full record

ArticleThe American journal of tropical medicine and hygiene2012

Evaluation of a rapid point-of-care fecal antigen detection test for Entamoeba histolytica.

Poonum S Korpe, Blake R Stott, Forida Nazib, Mamun Kabir, Rashidul Haque, Joel F Herbein, William A Petri

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Development of a salivary IgA detection method for accurate diagnosis of amebiasis.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  4. Accurate laboratory diagnosis of human intestinal and extra-intestinal amoebiasis.Gastroenterology and hepatology from bed to bench · 2022
    Review
  5. Article
  6. Article
  7. Update on laboratory diagnosis of amoebiasis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Review
  8. Article
  9. Article
  10. Article
  11. Entamoeba bangladeshi: An insight.Tropical parasitology · 2014
    Article
  12. G protein signaling in the parasite Entamoeba histolytica.Experimental & molecular medicine · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Poonum S KorpeDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22908-1337, USA. psk9p@virginia.edu
Blake R Stott
Forida Nazib
Mamun Kabir
Rashidul Haque
Joel F Herbein
William A Petri
University of Virginia · US

Funding

FIELD STUDIES OF IMMUNITY TO AMEBIASIS IN BANGLADESHR01AI043596 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CAROL A GILCHRIST, William A Petri · 1998 to 2026
$7.7M
Global Biothreats Training ProgramT32AI055432 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CRISS, ALISON K, PETRI, WILLIAM A · 2003 to 2022
$4.0M
New Rapid Diagnostic Tests for AmebiasisR42AI058450 · NIAID · TECHLAB, INC. · PI HERBEIN, JOEL F · 2006 to 2010
$4.0M
NIAID NIH HHS 5R42AI058450NIAID NIH HHS AI 43596NIAID NIH HHS R01 AI043596NIAID NIH HHS R42 AI058450NIAID NIH HHS T32 AI055432
6 · The paper itself

Abstract

Amebiasis is a major cause of morbidity and mortality in the developing world. A reliable point-of-care test would help to improve diagnosis and early treatment. We evaluated a novel rapid fecal antigen detection test for E. histolytica (E. HISTOLYTICA QUIK CHEK; TechLab, Inc., Blacksburg, VA), in a cohort of children in Bangladesh where amebiasis is endemic. This point-of-care test had a sensitivity of 100% and a specificity of 100% when compared with enzyme-linked immunosorbent assay antigen detection.

Indexed as

Point-of-Care SystemsAmebiasisAntigens, ProtozoanBangladeshChildChild, PreschoolEntamoeba histolyticaEnzyme-Linked Immunosorbent AssayFecesHumansInfantSensitivity and SpecificitySpecimen HandlingAntigens, Protozoan

Identifiers

PMID22665604
PMCPMC3366543
OpenAlexW2153266774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.