Evidence map›Paper›PMID 22665461›Full record

ArticleBMJ case reports2012

A 20-year-old Chinese man with recurrent hypokalemic periodic paralysis and delayed diagnosis.

Muniba Naqi, Vijaya Raj Bhatt, Shradha Pant, Rajesh Shrestha, Michael Tadros, Srujitha Murukutla, Jeffrey Rothman

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Muniba NaqiDepartment of Internal Medicine, Staten Island University Hospital, Staten Island, New York, USA.
Vijaya Raj Bhatt
Shradha Pant
Rajesh Shrestha
Michael Tadros
Srujitha Murukutla
Jeffrey Rothman
Northwell Health · USStaten Island University Hospital · USTribhuvan University · NPUniversity of Science and Technology Chittagong · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodic paralysis in the setting of hypokalemia can be the result of several underlying conditions, requiring systematic evaluation. Thyrotoxic periodic paralysis (TPP), a curable cause of hypokalemic periodic paralysis, can often be the first manifestation of thyrotoxicosis. Because the signs and symptoms of thyrotoxicosis can be subtle and clouded by the clinical distress of the patient, the diagnosis of the underlying metabolic disorder can be overlooked. The authors report a case of TPP in a young Chinese man in whom the diagnosis of thyrotoxicosis was initially missed. This case illustrates the lack of awareness of TPP among many physicians, delay in the diagnosis of TPP and the importance of performing thyroid function testing in all cases of periodic paralysis.

Indexed as

Delayed DiagnosisAntithyroid AgentsDiagnosis, DifferentialHumansHypokalemic Periodic ParalysisMaleMethimazoleThyrotoxicosisYoung AdultAntithyroid AgentsMethimazole

Identifiers

PMID22665461
PMCPMC3290970
OpenAlexW1979688356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.