ArticlePlant physiology2012
Brittle culm15 encodes a membrane-associated chitinase-like protein required for cellulose biosynthesis in rice.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 92 citations in OpenAlex.
- N-glycosylation code diversifies paralogous chitinases to balance plant immunity and growth.Nature plants · 2026Article
- Advances in Genes Associated with Straw Degradation in Rice.Life (Basel, Switzerland) · 2026Review
- Molecular insights into avocado grafting: the role of chitinase-like genes.Plant physiology · 2026Article
- Transcriptome based WGCNA analysis reveals the mechanisms underlying corolla abscission in blueberry (Vaccinium corymbosum L.).BMC plant biology · 2026Article
- The rice BRITTLE CULM 4 gene encodes a membrane protein affecting cellulose synthesis in the secondary cell wall.Plant & cell physiology · 2025Article
- Phenotypic and transcriptomic analysis reveals key genes associated with plant height in rubber tree and functional characterization of the candidate gene HbFLA11.The plant genome · 2025Article
- Subtilisin-like protease 4 regulates cold tolerance through cell wall modification in rice.Scientific reports · 2025Article
- Characterization of Cell Wall Compositions of Sodium Azide-Induced Brittle Mutant Lines in IR64 Variety and Its Potential Application.Plants (Basel, Switzerland) · 2024Article
- Re-localization of a repeat-containing fungal effector by apoplastic protein Chitinase-like 1 blocks its toxicity.Nature communications · 2024Article
- Genome-Wide Identification of a Maize Chitinase Gene Family and the Induction of Its Expression byGenes · 2024Article
- Identification and Analysis of the Mechanism of Stem Mechanical Strength Enhancement for Maize Inbred Lines QY1.International journal of molecular sciences · 2024Article
- Antagonistic functions of CTL1 and SUH1 mediate cell wall assembly inPlant direct · 2024Article
- Genome-Wide Identification and Expression Analysis of Chitinase Genes in Watermelon under Abiotic Stimuli andInternational journal of molecular sciences · 2024Article
- Chitinase-Like Protein PpCTL1 Contributes to Maintaining Fruit Firmness by Affecting Cellulose Biosynthesis during Peach Development.Foods (Basel, Switzerland) · 2023Article
- Isolation of a Novel QTL,International journal of molecular sciences · 2023Article
- Comprehensive identification and characterization of lncRNAs and circRNAs reveal potential brown planthopper-responsive ceRNA networks in rice.Frontiers in plant science · 2023Article
- Cell Wall Matrix Polysaccharides Contribute to Salt-Alkali Tolerance in Rice.International journal of molecular sciences · 2022Article
- Glycosylphosphatidylinositol anchor lipid remodeling directs proteins to the plasma membrane and governs cell wall mechanics.The Plant cell · 2022Article
- Integrated genetic analysis of leaf blast resistance in upland rice: QTL mapping, bulked segregant analysis and transcriptome sequencing.AoB PLANTS · 2022Article
- Golgi-Localized OsFPN1 is Involved in Co and Ni Transport and Their Detoxification in Rice.Rice (New York, N.Y.) · 2022Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant chitinases, a class of glycosyl hydrolases, participate in various aspects of normal plant growth and development, including cell wall metabolism and disease resistance. The rice (Oryza sativa) genome encodes 37 putative chitinases and chitinase-like proteins. However, none of them has been characterized at the genetic level. In this study, we report the isolation of a brittle culm mutant, bc15, and the map-based cloning of the BC15/OsCTL1 (for chitinase-like1) gene affected in the mutant. The gene encodes the rice chitinase-like protein BC15/OsCTL1. Mutation of BC15/OsCTL1 causes reduced cellulose content and mechanical strength without obvious alterations in plant growth. Bioinformatic analyses indicated that BC15/OsCTL1 is a class II chitinase-like protein that is devoid of both an amino-terminal cysteine-rich domain and the chitinase activity motif H-E-T-T but possesses an amino-terminal transmembrane domain. Biochemical assays demonstrated that BC15/OsCTL1 is a Golgi-localized type II membrane protein that lacks classical chitinase activity. Quantitative real-time polymerase chain reaction and β-glucuronidase activity analyses indicated that BC15/OsCTL1 is ubiquitously expressed. Investigation of the global expression profile of wild-type and bc15 plants, using Illumina RNA sequencing, further suggested a possible mechanism by which BC15/OsCTL1 mediates cellulose biosynthesis and cell wall remodeling. Our findings provide genetic evidence of a role for plant chitinases in cellulose biosynthesis in rice, which appears to differ from their roles as revealed by analysis of Arabidopsis (Arabidopsis thaliana).
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