Evidence map›Paper›PMID 22665237›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2012

Analytical methods for immunogenetic population data.

Steven J Mack, Pierre-Antoine Gourraud, Richard M Single, Glenys Thomson, Jill A Hollenbach

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. HLA Haplotype Frequencies and Genetic Profiles of the Kuwaiti Population.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Steven J MackCenter for Genetics, Children's Hospital and Research Center Oakland, Oakland, CA, USA. sjmack@chori.org
Pierre-Antoine Gourraud
Richard M Single
Glenys Thomson
Jill A Hollenbach

Funding

The Role of HLA and KIR in Rheumatoid Arthritis and Crohn's DiseaseU01AI067068 · NIAID · STANFORD UNIVERSITY · PI ERLICH, HENRY A, TRACHTENBERG, ELIZABETH A · 2005 to 2014
$10.9M
Systemic Lupus Erythematosus and Ulcerative Colitis StudyU19AI067152 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VYSE, TIMOTHY JAMES · 2005 to 2009
$10.1M
NIAID NIH HHS N01 AI040076NIAID NIH HHS U01 AI067068NIAID NIH HHS U01AI067068NIAID NIH HHS U19 AI067152
6 · The paper itself

Abstract

In this chapter, we describe analyses commonly applied to immunogenetic population data, along with software tools that are currently available to perform those analyses. Where possible, we focus on tools that have been developed specifically for the analysis of highly polymorphic immunogenetic data. These analytical methods serve both as a means to examine the appropriateness of a dataset for testing a specific hypothesis, as well as a means of testing hypotheses. Rather than treat this chapter as a protocol for analyzing any population dataset, each researcher and analyst should first consider their data, the possible analyses, and any available tools in light of the hypothesis being tested. The extent to which the data and analyses are appropriate to each other should be determined before any analyses are performed.

Indexed as

Databases, GeneticHistocompatibility TestingHLA AntigensHumansImmunogeneticsPolymorphism, GeneticSoftwareHLA Antigens

Identifiers

PMID22665237
PMCPMC4209087

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.