Evidence map›Paper›PMID 22664983›Full record

ReviewNature structural & molecular biology2012

One core, two shells: bacterial and eukaryotic ribosomes.

Sergey Melnikov, Adam Ben-Shem, Nicolas Garreau de Loubresse, Lasse Jenner, Gulnara Yusupova, Marat Yusupov

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature structural & molecular biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 260 papers.

0numbers the graph read from it
0cells of the map it votes in
260citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

260 citing papers in PubMed.

  1. Article
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  5. The Origins of GPCRs.International journal of molecular sciences · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
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  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article

200 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sergey MelnikovInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.
Adam Ben-Shem
Nicolas Garreau de Loubresse
Lasse Jenner
Gulnara Yusupova
Marat Yusupov

Funding

European Research Council 294312
6 · The paper itself

Abstract

Ribosomes are universally conserved enzymes that carry out protein biosynthesis. Bacterial and eukaryotic ribosomes, which share an evolutionarily conserved core, are thought to have evolved from a common ancestor by addition of proteins and RNA that bestow different functionalities to ribosomes from different domains of life. Recently, structures of the eukaryotic ribosome, determined by X-ray crystallography, have allowed us to compare these structures to previously determined structures of bacterial ribosomes. Here we describe selected bacteria- or eukaryote-specific structural features of the ribosome and discuss the functional implications of some of them.

Indexed as

AnimalsBacteriaEukaryotic CellsHumansModels, MolecularProtein BiosynthesisRibosomal ProteinsRibosomesRNA, RibosomalRibosomal ProteinsRNA, Ribosomal

Identifiers

PMID22664983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.