Evidence map›Paper›PMID 22664746›Full record

ArticleResuscitation2012

Endotracheal intubation versus supraglottic airway insertion in out-of-hospital cardiac arrest.

Henry E Wang, Daniel Szydlo, John A Stouffer, Steve Lin, Jestin N Carlson, Christian Vaillancourt, Gena Sears, Richard P Verbeek, Raymond Fowler, Ahamed H Idris and 6 more

Registry-linked trialAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Resuscitation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02240901 (Effectiveness and Pulmonary Complications of Peri-Operative Laryngeal Mask Airway Used in Elderly Patients), which is not on this map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02240901 nacompletednot on this mapstarted 2016, after this paper: background citation

Effectiveness and Pulmonary Complications of Peri-Operative Laryngeal Mask Airway Used in Elderly Patients(POLMA-EP Trial): a Multi-center Randomized Controlled Clinical Trial

TypeinterventionalSponsorRenJi HospitalRan2016 to 2020Enrolled2,900ConditionsComplications, SurgeryArmsLaryngeal mask airway(LMA), Endotracheal intubation(ETI)
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 162 citations in OpenAlex.

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  11. Contemporary issues in pediatric prehospital airway management.Expert review of respiratory medicine · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 2 countries.

Henry E WangDepartment of Emergency Medicine, University of Alabama at Birmingham, Birmingham, AL 35249, USA. hwang@uabmc.edu
Daniel Szydlo
John A Stouffer
Steve Lin
Jestin N Carlson
Christian Vaillancourt
Gena Sears
Richard P Verbeek
Raymond Fowler
Ahamed H Idris
Karl Koenig
James Christenson
Anushirvan Minokadeh
Joseph Brandt
Thomas Rea
ROC Investigators
University of Washington · USThe University of Texas Southwestern Medical Center · USUniversity of Toronto · CAClackamas Community College · USMedical College of Wisconsin · USOregon Health & Science University · USUniversity of Alabama at Birmingham · USUniversity of British Columbia · CAUniversity of California San Diego · USUniversity of Ottawa · CAUniversity of Pittsburgh · US

Funding

Resuscitation Outcomes Consortium (ROC) Data Coordinating CenterU01HL077863 · NHLBI · UNIVERSITY OF WASHINGTON · PI MAY, SUSANNE · 2004 to 2015
$125.1M
Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-PittsburghU01HL077871 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CALLAWAY, CLIFTON W. · 2004 to 2015
$4.0M
Southeastern Resucitation Research CenterU01HL077881 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KERBY, JEFFREY D, WANG, HENRY E. · 2004 to 2015
$3.9M
Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-PortlandU01HL077873 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI DAYA, MOHAMUD RAMZANALI · 2004 to 2015
$3.9M
Resuscitation Outcomes Consortium Regional Clinical Center-DFW Center for ResusciU01HL077887 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI IDRIS, AHAMED H · 2004 to 2015
$3.2M
Resuscitation Outcomes Consortium (ROC) Regional Clinical Centers-MilwaukeeU01HL077866 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI AUFDERHEIDE, TOM PAUL · 2004 to 2015
$3.0M
Seattle-King County Center for Resuscitation ResearchU01HL077867 · NHLBI · UNIVERSITY OF WASHINGTON · PI KUDENCHUK, PETER JAMES · 2004 to 2015
$3.0M
The UCSD/San Diego Resuscitation Research CenterU01HL077908 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VILKE, GARY · 2004 to 2015
$2.9M
Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-OTTAWA-OPALS-BCRU01HL077885 · NHLBI · OTTAWA HOSPITAL RESEARCH INSTITUTE · PI STIELL, IAN G. · 2004 to 2015
$2.4M
Resuscitation Outcomes Consortium (ROC) Regional Clinical Center-Toronto RegionalU01HL077872 · NHLBI · ST. MICHAEL'S HOSPITAL · PI MORRISON, LAURIE · 2004 to 2015
$1.9M
CIHRNHLBI NIH HHS 5U01 HL077863NHLBI NIH HHS HL077866NHLBI NIH HHS HL077867NHLBI NIH HHS HL077871NHLBI NIH HHS HL077872NHLBI NIH HHS HL077873NHLBI NIH HHS HL077881NHLBI NIH HHS HL077885NHLBI NIH HHS HL077887NHLBI NIH HHS HL077908NHLBI NIH HHS U01 HL077863NHLBI NIH HHS U01 HL077866NHLBI NIH HHS U01 HL077867NHLBI NIH HHS U01 HL077871NHLBI NIH HHS U01 HL077872NHLBI NIH HHS U01 HL077873NHLBI NIH HHS U01 HL077881NHLBI NIH HHS U01 HL077885NHLBI NIH HHS U01 HL077887NHLBI NIH HHS U01 HL077908
6 · The paper itself

Abstract

objectiveTo simplify airway management and minimize cardiopulmonary resuscitation (CPR) chest compression interruptions, some emergency medical services (EMS) practitioners utilize supraglottic airway (SGA) devices instead of endotracheal intubation (ETI) as the primary airway adjunct in out-of-hospital cardiac arrest (OHCA). We compared the outcomes of patients receiving ETI with those receiving SGA following OHCA.

methodsWe performed a secondary analysis of data from the multicenter Resuscitation Outcomes Consortium (ROC) PRIMED trial. We studied adult non-traumatic OHCA receiving successful SGA insertion (King Laryngeal Tube, Combitube, and Laryngeal Mask Airway) or successful ETI. The primary outcome was survival to hospital discharge with satisfactory functional status (Modified Rankin Scale ≤3). Secondary outcomes included return of spontaneous circulation (ROSC), 24-h survival, major airway or pulmonary complications (pulmonary edema, internal thoracic or abdominal injuries, acute lung injury, sepsis, and pneumonia). Using multivariable logistic regression, we studied the association between out-of-hospital airway management method (ETI vs. SGA) and OHCA outcomes, adjusting for confounders.

resultsOf 10,455 adult OHCA, 8487 (81.2%) received ETI and 1968 (18.8%) received SGA. Survival to hospital discharge with satisfactory functional status was: ETI 4.7%, SGA 3.9%. Compared with successful SGA, successful ETI was associated with increased survival to hospital discharge (adjusted OR 1.40; 95% CI: 1.04, 1.89), ROSC (adjusted OR 1.78; 95% CI: 1.54, 2.04) and 24-h survival (adjusted OR 1.74; 95% CI: 1.49, 2.04). ETI was not associated with secondary airway or pulmonary complications (adjusted OR 0.84; 95% CI: 0.61, 1.16).

conclusionsIn this secondary analysis of data from the multicenter ROC PRIMED trial, ETI was associated with improved outcomes over SGA insertion after OHCA.

Indexed as

GlottisIntubation, IntratrachealAgedFemaleHumansIntubationMaleMiddle AgedOut-of-Hospital Cardiac ArrestProspective StudiesTreatment Outcome

Identifiers

PMID22664746
PMCPMC3733371
OpenAlexW2138377425

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.