Evidence map›Paper›PMID 22663941›Full record

ArticleInternational journal of circumpolar health2012

Incidence of pancreatic cancer in Greenland 2000-2010.

Jakob Kirkegaard

Registry-linked trialOpen access · goldAbstract readComparative Study
In one paragraph

Article in International journal of circumpolar health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05595811 (The Outcome After Operation for Pancreatic and Periampullary Tumors in Greeland Inuit.), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05595811 completednot on this map

The Outcome After Operation for Pancreatic and Periampullary Tumors in Greeland Inuit.

TypeobservationalSponsorRigshospitalet, DenmarkRan1999 to 2021Enrolled2,326ConditionsPancreatic Neoplasms, Periampullary NeoplasmsArmsoutcome following surgery
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jakob KirkegaardUniversity of Aarhus, Aarhus C, Denmark. kirkegaard@studmed.au.dk
Aarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInuit people are known to be at an increased risk of cancers usually uncommon to the western world such as cancers of the nasopharynx and salivary glands. But what is the trend regarding pancreatic cancer?

objectiveTo determine the incidence of pancreatic cancer (PC) in Greenland compared with Denmark in the period 2000-2010. STUDY

designRetrospective register-based study. Cases were retrieved from The Danish Cancer Register and The Greenlandic Patient Register and stratified in 5-year age intervals for each year. Age-standardized incidence ratios (SIR) for each year for Greenland compared with Denmark were calculated using the number of cases and the number of inhabitants in each 5-year age interval and in each country. The average SIR for the entire period was calculated using a weighted average.

resultsThe study revealed a SIR of 2.38 (95% CI: 1.97-2.86; p<0.0001) indicating a significantly increased incidence of PC in Greenland compared with Denmark. A linear regression analysis showed no significant change in the SIR over time (p for trend 0.25) as well as no significant change isolated in Greenland (p for trend 0.8). Furthermore, the Inuit were significantly younger at the time of diagnosis (mean 62.7 vs. 70.0; p<0.0001).

conclusionsThe age-standardized incidence of PC is 138% higher in Greenland than in Denmark. A part of this could be explained by a higher prevalence of smoking and DM-2. However, the impact of genetic factors cannot be disregarded and should be subjected to further investigation.

Indexed as

AdolescentAdultAgedChildChild, PreschoolDenmarkFemaleGreenlandHumansInfantMaleMiddle AgedPancreatic NeoplasmsRetrospective StudiesYoung Adult

Identifiers

PMID22663941
PMCPMC3417692
OpenAlexW1993015641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.