ArticlePloS one2012
A metabolomic approach to the study of wine micro-oxygenation.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Influence of Oxygen Management on Color and Phenolics of Red Wines.Molecules (Basel, Switzerland) · 2023Article
- Sulfonation Reactions behind the Fate of White Wine's Shelf-Life.Metabolites · 2022Article
- Characterization of Cabernet Sauvignon Wines by Untargeted HS-SPME GC-QTOF-MS.Molecules (Basel, Switzerland) · 2022Article
- LC-MS-Based Metabolomics Discriminates Premium from Standard Chilean cv. Cabernet Sauvignon Wines from Different Valleys.Metabolites · 2021Article
- Use of Untargeted Liquid Chromatography-Mass Spectrometry Metabolome To Discriminate Italian Monovarietal Red Wines, Produced in Their Different Terroirs.Journal of agricultural and food chemistry · 2020Article
- Effect of Musts Oxygenation at Various Stages of Cider Production on Oenological Parameters, Antioxidant Activity, and Profile of Volatile Cider Compounds.Biomolecules · 2020Article
- Non-Targeted Metabolite Profiles and Sensory Properties Elucidate Commonalities and Differences of Wines Made with the Same Variety but Different Cultivar Clones.Metabolites · 2020Article
- The impact of SOScientific reports · 2018Article
- Molecular and Macromolecular Changes in Bottle-Aged White Wines Reflect Oxidative Evolution-Impact of Must Clarification and Bottle Closure.Frontiers in chemistry · 2018Article
- The Hidden Face of Wine Polyphenol Polymerization Highlighted by High-Resolution Mass Spectrometry.ChemistryOpen · 2017Article
- Sunlight Modulates Fruit Metabolic Profile and Shapes the Spatial Pattern of Compound Accumulation within the Grape Cluster.Frontiers in plant science · 2017Article
- Chemical messages from an ancient buried bottle: metabolomics for wine archeochemistry.NPJ science of food · 2017Article
- MetICA: independent component analysis for high-resolution mass-spectrometry based non-targeted metabolomics.BMC bioinformatics · 2016Article
- Metabolite profiling and transcript analysis reveal specificities in the response of a berry derived cell culture to abiotic stresses.Frontiers in plant science · 2015Article
- Study of Grape Polyphenols by Liquid Chromatography-High-Resolution Mass Spectrometry (UHPLC/QTOF) and Suspect Screening Analysis.Journal of analytical methods in chemistry · 2015Article
- Metabolite and transcript profiling of berry skin during fruit development elucidates differential regulation between Cabernet Sauvignon and Shiraz cultivars at branching points in the polyphenol pathway.BMC plant biology · 2014Article
- High precision mass measurements for wine metabolomics.Frontiers in chemistry · 2014Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wine micro-oxygenation is a globally used treatment and its effects were studied here by analysing by untargeted LC-MS the wine metabolomic fingerprint. Eight different procedural variations, marked by the addition of oxygen (four levels) and iron (two levels) were applied to Sangiovese wine, before and after malolactic fermentation. Data analysis using supervised and unsupervised multivariate methods highlighted some known candidate biomarkers, together with a number of metabolites which had never previously been considered as possible biomarkers for wine micro-oxygenation. Various pigments and tannins were identified among the known candidate biomarkers. Additional new information was obtained suggesting a correlation between oxygen doses and metal contents and changes in the concentration of primary metabolites such as arginine, proline, tryptophan and raffinose, and secondary metabolites such as succinic acid and xanthine. Based on these findings, new hypotheses regarding the formation and reactivity of wine pigment during micro-oxygenation have been proposed. This experiment highlights the feasibility of using unbiased, untargeted metabolomic fingerprinting to improve our understanding of wine chemistry.
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