ArticleBiomicrofluidics2011
Membrane-integrated microfluidic device for high-resolution live cell imaging.
Article in Biomicrofluidics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- A neurovascular unit-on-a-chip: culture and differentiation of human neural stem cells in a three-dimensional microfluidic environment.Neural regeneration research · 2022Article
- An Interphase Microfluidic Culture System for the Study of Ex Vivo Intestinal Tissue.Micromachines · 2020Article
- A simple cell transport device keeps culture alive and functional during shipping.Biotechnology progress · 2017Article
- Large-Scale Integration of All-Glass Valves on a Microfluidic Device.Micromachines · 2016Article
- Microphysical space of a liver sinusoid device enables simplified long-term maintenance of chimeric mouse-expanded human hepatocytes.Biomedical microdevices · 2014Article
- Review
- Stable chemical bonding of porous membranes and poly(dimethylsiloxane) devices for long-term cell culture.Biomicrofluidics · 2014Article
- Article
- Topographically-patterned porous membranes in a microfluidic device as an in vitro model of renal reabsorptive barriers.Lab on a chip · 2013Article
- A hybrid microfluidic platform for cell-based assays via diffusive and convective trans-membrane perfusion.Biomicrofluidics · 2013Article
- High yield fabrication of multilayer polydimethylsiloxane [corrected] devices with freestanding micropillar arrays.Biomicrofluidics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The design and fabrication of a membrane-integrated microfluidic cell culture device (five layers,≤500 μm total thickness) developed for high resolution microscopy is reported here. The multi-layer device was constructed to enable membrane separated cell culture for tissue mimetic in vitro model applications and pharmacodynamic evaluation studies. The microdevice was developed via a unique combination of low profile fluidic interconnect design, substrate transfer methodology, and wet silane bonding. To demonstrate the unique high resolution imaging capability of this device, we used oil immersion microscopy to image stained nuclei and mitochondria in primary hepatocytes adhered to the incorporated membrane.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.