ArticleFrontiers in plant science2012
MicroRNAs as regulators in plant metal toxicity response.
Article in Frontiers in plant science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 96 citations in OpenAlex.
- Response to Cadmium Toxicity: Orchestration of Polyamines and microRNAs in Maize Plant.Plants (Basel, Switzerland) · 2023Article
- Systems biology of chromium-plant interaction: insights from omics approaches.Frontiers in plant science · 2023Review
- The miR393-Target Module Regulates Plant Development and Responses to Biotic and Abiotic Stresses.International journal of molecular sciences · 2022Review
- microRNAs: Key Players in Plant Response to Metal Toxicity.International journal of molecular sciences · 2022Review
- Is Genetic Engineering a Route to Enhance Microalgae-Mediated Bioremediation of Heavy Metal-Containing Effluents?Molecules (Basel, Switzerland) · 2022Review
- TIR1/AFB proteins: Active players in abiotic and biotic stress signaling.Frontiers in plant science · 2022Review
- Recent advances in physiological and molecular mechanisms of heavy metal accumulation in plants.Environmental science and pollution research international · 2021Review
- Robinsonecio gerberifolius as a sentinel organism for atmospheric pollution by heavy metals in several sites of Mexico city and its metropolitan area.Environmental science and pollution research international · 2021Article
- MicroRNA-Mediated Responses to Cadmium Stress inPlants (Basel, Switzerland) · 2021Article
- MicroRNA-Mediated Responses to Chromium Stress Provide Insight Into Tolerance Characteristics ofFrontiers in plant science · 2021Article
- Toxic-Metal-Induced Alteration in miRNA Expression Profile as a Proposed Mechanism for Disease Development.Cells · 2020Review
- Modulation of Plant and Fungal Gene Expression Upon Cd Exposure and Symbiosis in Ericoid MycorrhizalFrontiers in microbiology · 2020Article
- Tolerance of Iron-Deficient and -Toxic Soil Conditions in Rice.Plants (Basel, Switzerland) · 2019Review
- miR393s regulate salt stress response pathway in Arabidopsis thaliana through scaffold protein RACK1A mediated ABA signaling pathways.Plant signaling & behavior · 2019Article
- Morphological and functional responses of a metal-tolerant sunflower mutant line to a copper-contaminated soil series.Environmental science and pollution research international · 2018Article
- Indicators of environmental contamination by heavy metals in leaves of Taraxacum officinale in two zones of the metropolitan area of Mexico City.Environmental science and pollution research international · 2018Article
- Auxin signaling: a big question to be addressed by small molecules.Journal of experimental botany · 2018Review
- miR394 Acts as a Negative Regulator ofFrontiers in plant science · 2018Article
- Review
- Ectopic expression of CSD1 and CSD2 targeting genes of miR398 in grapevine is associated with oxidative stress tolerance.Functional & integrative genomics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metal toxicity is a major stress affecting crop production. This includes metals that are essential for plants (copper, iron, zinc, manganese), and non-essential metals (cadmium, aluminum, cobalt, mercury). A primary common effect of high concentrations of metal such as aluminum, copper, cadmium, or mercury is root growth inhibition. Metal toxicity triggers the accumulation of reactive oxygen species leading to damage of lipids, proteins, and DNA. The plants response to metal toxicity involves several biological processes that require fine and precise regulation at transcriptional and post-transcriptional levels. MicroRNAs (miRNAs) are 21 nucleotide non-coding RNAs that regulate gene expression at the post-transcriptional level. A miRNA, incorporated into a RNA-induced silencing complex, promotes cleavage of its target mRNA that is recognized by an almost perfect base complementarity. In plants, miRNA regulation is involved in development and also in biotic and abiotic stress responses. We review novel advances in identifying miRNAs related to metal toxicity responses and their potential role according to their targets. Most of the targets for plant metal-responsive miRNAs are transcription factors. Information about metal-responsive miRNAs in different plants points to important regulatory roles of miR319, miR390, miR393, and miR398. The target of miR319 is the TCP transcription factor, implicated in growth control. miR390 exerts its action through the biogenesis of trans-acting small interference RNAs that, in turn, regulate auxin responsive factors. miR393 targets the auxin receptors TIR1/AFBs and a bHLH transcription factor. Increasing evidence points to the crucial role of miR398 and its targets Cu/Zn superoxide dismutases in the control of the oxidative stress generated after high copper or iron exposure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.