ArticleThe Journal of biological chemistry2012
Functional characterization of the FoxE iron oxidoreductase from the photoferrotroph Rhodobacter ferrooxidans SW2.
Article in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Iron binding before iron limitation: siderophore synthesis arose well before iron became a limiting element.ISME communications · 2026Article
- Single Phototrophic Bacterium-Mediated Iron Cycling in Aquatic Environments.Research (Washington, D.C.) · 2024Article
- Protein Interactions inMolecules (Basel, Switzerland) · 2023Article
- Review
- An evolving view on biogeochemical cycling of iron.Nature reviews. Microbiology · 2021Review
- A physiological perspective on the origin and evolution of photosynthesis.FEMS microbiology reviews · 2018Review
- Photoferrotrophy: Remains of an Ancient Photosynthesis in Modern Environments.Frontiers in microbiology · 2017Review
- Study of the succession of microbial communities for sulfur cycle response to ecological factors change in sediment of sewage system.Environmental science and pollution research international · 2015Article
- Genetic and biochemical investigations of the role of MamP in redox control of iron biomineralization in Magnetospirillum magneticum.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- The interplay of microbially mediated and abiotic reactions in the biogeochemical Fe cycle.Nature reviews. Microbiology · 2014Review
- Ligand-enhanced abiotic iron oxidation and the effects of chemical versus biological iron cycling in anoxic environments.Environmental science & technology · 2013Article
- Iron homeostasis in theAdvances in botanical research · 2013Article
- Genome-enabled studies of anaerobic, nitrate-dependent iron oxidation in the chemolithoautotrophic bacterium Thiobacillus denitrificans.Frontiers in microbiology · 2013Article
- Crystallization and preliminary crystallographic studies of FoxE from Rhodobacter ferrooxidans SW2, an Fe(II) oxidoreductase involved in photoferrotrophy.Acta crystallographica. Section F, Structural biology and crystallization communications · 2012Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Photoferrotrophy is presumed to be an ancient type of photosynthetic metabolism in which bacteria use the reducing power of ferrous iron to drive carbon fixation. In this work the putative iron oxidoreductase of the photoferrotroph Rhodobacter ferrooxidans SW2 was cloned, purified, and characterized for the first time. This protein, FoxE, was characterized using spectroscopic, thermodynamic, and kinetic techniques. It is a c-type cytochrome that forms a trimer or tetramer in solution; the two hemes of each monomer are hexacoordinated by histidine and methionine. The hemes have positive reduction potentials that allow downhill electron transfer from many geochemically relevant ferrous iron forms to the photosynthetic reaction center. The reduction potentials of the hemes are different and are cross-assigned to fast and slow kinetic phases of ferrous iron oxidation in vitro. Lower reactivity was observed at high pH and may contribute to prevent ferric iron precipitation inside or at the surface of the cell. These results help fill in the molecular details of a metabolic process that likely contributed to the deposition of precambrian banded iron formations, globally important sedimentary rocks that are found on every continent today.
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