Evidence map›Paper›PMID 22660977›Full record

ReviewFrontiers of medicine2012

Nucleic acid-based diagnostics for infectious diseases in public health affairs.

Albert Cheung-Hoi Yu, Greg Vatcher, Xin Yue, Yan Dong, Mao Hua Li, Patrick H K Tam, Parker Y L Tsang, April K Y Wong, Michael H K Hui, Bin Yang and 2 more

Abstract readReview
In one paragraph

Review in Frontiers of medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Nucleic Acid Prevalence of ZoonoticTropical medicine and infectious disease · 2023
    Review
  8. Review
  9. Review
  10. 3'International journal of molecular sciences · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. The changing culture of the microbiology laboratory.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Albert Cheung-Hoi YuNeuroscience Research Institute, Department of Neurobiology, School of Basic Medical Sciences, Key Laboratory for Neuroscience, Peking University, Beijing, 100191, China. achy@haikanglife.com
Greg Vatcher
Xin Yue
Yan Dong
Mao Hua Li
Patrick H K Tam
Parker Y L Tsang
April K Y Wong
Michael H K Hui
Bin Yang
Hao Tang
Lok-Ting Lau

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diseases, mostly caused by bacteria and viruses but also a result of fungal and parasitic infection, have been one of the most important public health concerns throughout human history. The first step in combating these pathogens is to get a timely and accurate diagnosis at an affordable cost. Many kinds of diagnostics have been developed, such as pathogen culture, biochemical tests and serological tests, to help detect and fight against the causative agents of diseases. However, these diagnostic tests are generally unsatisfactory because they are not particularly sensitive and specific and are unable to deliver speedy results. Nucleic acid-based diagnostics, detecting pathogens through the identification of their genomic sequences, have shown promise to overcome the above limitations and become more widely adopted in clinical tests. Here we review some of the most popular nucleic acid-based diagnostics and focus on their adaptability and applicability to routine clinical usage. We also compare and contrast the characteristics of different types of nucleic acid-based diagnostics.

Indexed as

Communicable DiseasesHumansNucleic Acid Amplification TechniquesOligonucleotide Array Sequence AnalysisPolymerase Chain ReactionPublic HealthSelf-Sustained Sequence Replication

Identifiers

PMID22660977
PMCPMC7088663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.