ArticlePediatric nephrology (Berlin, Germany)2012
Vitamin D status of children receiving chronic dialysis.
Article in Pediatric nephrology (Berlin, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 8 citations in OpenAlex.
- Low serum levels of vitamin D are associated with anxiety in children and adolescents with dialysis.Scientific reports · 2018Article
- Matrix Metalloproteinase (MMP)-9 Levels in Children on Hemodialysis: Association with MMP-9 CInternational journal of biomedical science : IJBS · 2016Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients receiving chronic dialysis therapy are presumed to be at risk for 25(OH) D(3) deficiency, but little information is available on its prevalence, manifestations of deficiency, and the impact of ergocalciferol supplementation.
methodsA single-center, retrospective study of 51 prevalent pediatric patients on hemodialysis or peritoneal dialysis was conducted to address these issues.
resultsForty of 51 (78.4 %) patients had low (<30 ng/ml) 25(OH) D(3) levels. Of these, 2 % had values < 5 ng/ml, 41.2 % 5-15 ng/ml, and 35.3 % 16-30 ng/ml. Age >12 years, non-Caucasian race and > 12-month duration of dialysis were significantly associated with low 25(OH) D(3) levels (p = 0.006, p = 0.05, and p = 0.04, respectively). Twenty-three of the 40 patients deficient in 25(OH) D(3) received repletion therapy with ergocalciferol and had a follow-up level at an average of 2 months following completion of a single course of therapy; 14 (60 %) of the levels were normal. Mean baseline intact parathyroid hormone (iPTH) for patients with 25(OH) D(3) levels ≤ 30 was 478.68 ± 474.01 pg/ml and treatment with ergocalciferol was not associated with a significant decrease in the mean iPTH value (p = 0.45).
conclusionsWe conclude that low 25(OH) D(3) levels are common in pediatric patients receiving dialysis and require attention in accordance with current practice guidelines.
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