Evidence map›Paper›PMID 22660443›Full record

ReviewEuropean journal of clinical pharmacology2013

Azole interactions with multidrug therapy in pediatric oncology.

Antonio Ruggiero, Roberta Arena, Andrea Battista, Daniela Rizzo, Giorgio Attinà, Riccardo Riccardi

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in European journal of clinical pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Antonio RuggieroPediatric Oncology Division, "A. Gemelli" Hospital, Catholic University of Rome, Largo A. Gemelli, 00168 Rome, Italy. ruggiero@rm.unicatt.it
Roberta Arena
Andrea Battista
Daniela Rizzo
Giorgio Attinà
Riccardo Riccardi
Inserm · FRSanté Publique France · FRUniversité Claude Bernard Lyon 1 · FRVictor (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with cancer receive multidrug therapy. Antineoplastic agents and supportive care drugs are often administered together, leading to potential drug-drug interactions. These interactions may have significant clinical implications in terms of toxicity or a decrease in the efficacy of the treatment administered. Here, we focus on the role of azoles and their main pharmacokinetic interactions with the principal classes of drugs used in pediatric oncology. The co-administration of azoles and antineoplastic agents, corticosteroids, immunosuppressants, antacids, antiemetics, antiepileptic drugs and analgesics was investigated, and a practical guide on the management of these drugs when administered together is provided.

Indexed as

Drug InteractionsAdrenal Cortex HormonesAntacidsAnticonvulsantsAntiemeticsAntifungal AgentsAntineoplastic AgentsAzolesChildDrug Therapy, CombinationHumansImmunosuppressive AgentsNeoplasmsAdrenal Cortex HormonesAntacidsAnticonvulsantsAntiemeticsAntifungal AgentsAntineoplastic AgentsAzolesImmunosuppressive Agents

Identifiers

PMID22660443
OpenAlexW2056917744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.