Evidence map›Paper›PMID 22658837›Full record

ReviewCurrent opinion in cell biology2012

Polarity and lymphocyte fate determination.

John T Chang

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. CD4 T-cell memory generation and maintenance.Critical reviews in immunology · 2014
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

John T ChangDepartment of Medicine, University of California San Diego, La Jolla, CA, USA. changj@ucsd.edu

Funding

Regulation and Function of Polarity and Asymmetric Cell Division in ImmunityR01AI095277 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHANG, JOHN T · 2012 to 2016
$2.6M
Understanding the Basis for Cellular Diversity During Adaptive ImmunityDP2OD008469 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHANG, JOHN T · 2011 to 2011
$2.3M
Asymmetric T cell division initiating adaptive immunity and colitisK08DK080949 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI CHANG, JOHN T · 2008 to 2012
$723k
Howard Hughes Medical InstituteNIAID NIH HHS AI095277NIAID NIH HHS R01 AI095277NIDDK NIH HHS DK080949NIDDK NIH HHS K08 DK080949NIH HHS DP2 OD008469NIH HHS OD008469
6 · The paper itself

Abstract

Polarity within lymphocytes has been recognized to regulate a variety of processes, including migration, signaling, and the execution of effector function. It has been recently proposed, however, that this polarized behavior may also serve a different purpose in lymphocytes that have not yet encountered their foreign antigen-to coordinate asymmetric cell division. Asymmetric division is an evolutionarily conserved mechanism allowing a single cell to give rise to two distinct daughter cells from inception. In this review, recent findings in polarity and asymmetric division in lymphocytes are discussed.

Indexed as

Asymmetric Cell DivisionCell LineageCell PolarityAnimalsHumansLymphocytesSignal Transduction

Identifiers

PMID22658837
PMCPMC3425726

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.