ArticleFrontiers in oncology2012
Current status and future perspectives on the etiology of esophageal adenocarcinoma.
Article in Frontiers in oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Association between diabetes mellitus and gastroesophageal reflux disease: A meta-analysis.World journal of gastroenterology · 2015Pooled it
- A human Barrett's esophagus organoid system reveals epithelial-mesenchymal plasticity induced by acid and bile salts.American journal of physiology. Gastrointestinal and liver physiology · 2022Article
- Esophageal cancer: Epidemiology, risk factors and screening.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2021Article
- Key molecules involved in the Th17/Treg balance are associated with the pathogenesis of reflux esophagitis and Barrett's esophagus.Esophagus : official journal of the Japan Esophageal Society · 2021Article
- Prior tonsillectomy is associated with an increased risk of esophageal adenocarcinoma.PloS one · 2020Article
- Article
- Columnar-Lined Esophagus Develops via Wound Repair in a Surgical Model of Reflux Esophagitis.Cellular and molecular gastroenterology and hepatology · 2018Article
- Reflux esophagitis and its role in the pathogenesis of Barrett's metaplasia.Journal of gastroenterology · 2017Review
- Article
- NOD-Like Receptor Protein 3 Inflammasome Priming and Activation in Barrett's Epithelial Cells.Cellular and molecular gastroenterology and hepatology · 2016Article
- Mitochondrial STAT3 contributes to transformation of Barrett's epithelial cells that express oncogenic Ras in a p53-independent fashion.American journal of physiology. Gastrointestinal and liver physiology · 2015Article
- Biomarkers for dysplastic Barrett's: ready for prime time?World journal of surgery · 2015Review
- Beyond the stomach: an updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment.World journal of gastroenterology · 2014Review
- Diet and lifestyle factors and risk of subtypes of esophageal and gastric cancers: classification tree analysis.Annals of epidemiology · 2014Article
- Targeting chemokine pathways in esophageal adenocarcinoma.Cell cycle (Georgetown, Tex.) · 2014Article
- Case Report: Detection and quantification of tumor cells in peripheral blood and ascitic fluid from a metastatic esophageal cancer patient using the CellSearch (®) technology.F1000Research · 2014Article
- Upper gastrointestinal cancer and reflux disease.Journal of gastric cancer · 2013Article
- Targeted treatments for metastatic esophageal squamous cell cancer.World journal of gastrointestinal oncology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Esophageal adenocarcinoma is the most common type of esophageal cancer in most Western countries and is an important contributor to overall cancer mortality. Most cases of esophageal adenocarcinoma are believed to arise from Barrett's esophagus. Esophageal adenocarcinoma occurs more frequently in white men over 50 years old, as well as in people with frequent symptoms of gastroesophageal reflux, in smokers and in people who are obese. Higher consumption of fruit and vegetables, use of non-steroidal anti-inflammatory drugs, and infection with Helicobacter pylori have all been shown to reduce the risk of esophageal adenocarcinoma. Here, we review the epidemiological evidence for the major risk factors of esophageal adenocarcinoma and also discuss perspectives for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.