ArticleEvidence-based complementary and alternative medicine : eCAM2012
Role of mesotherapy in musculoskeletal pain: opinions from the italian society of mesotherapy.
Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Comparison o the Efficacy of Mesotherapy and Intra-articular Steroid Injection in Patients With Chronic Shoulder Pain
Comparison of the Efficacy of Mesotherapy and Extracorporeal Shock Wave Therapy in Patients With Lateral Epicondylitis: A Prospective Randomised Controlled Trial
Comparison of Mesotherapy Treatment Doses in Patients With Chronic Non-Specific Neck Pain: A Randomised Controlled Double-Blind Clinical Trial
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Safety and efficacy of mesotherapy in musculoskeletal disorders: A systematic review of randomized controlled trials with meta-analysis.Journal of rehabilitation medicine · 2021Pooled it
- Comparison of Mesotherapy and Transcutaneous Electrical Nerve Stimulation (TENS) in the Management of Chronic Non-Specific Low Back Pain: A Randomized Clinical Trial.La Tunisie medicale · 2025Trial
- Efficacy of Mesotherapy for Pain, Function and Quality of Life in Patients with Mild and Moderate Knee Osteoarthritis: A Randomized Controlled Trial.Journal of musculoskeletal & neuronal interactions · 2023Trial
- Pes Anserine Bursitis in Symptomatic Osteoarthritis Patients: A Mesotherapy Treatment Study.Journal of alternative and complementary medicine (New York, N.Y.) · 2015Trial
- Intradermal mesotherapy versus intravenous dexketoprofen for the treatment of migraine headache without aura: a randomized controlled trial.Annals of Saudi medicineTrial
- Efficacy of mesotherapy in patients with acute and subacute neck pain: A randomized controlled trial.Turkish journal of physical medicine and rehabilitation · 2026Article
- International Consensus Guidelines on the Safe and Evidence-Based Practice of Mesotherapy: A Multidisciplinary Statement.Journal of clinical medicine · 2025Article
- Upper Crossed Syndrome and Scapulae Upper-Trapping: A Mesotherapy Protocol in Cervicoscapulobrachial Pain-The 8:1 Block.Bioengineering (Basel, Switzerland) · 2024Article
- The Role of Rehabilitation after Spinal Mesotherapy in a Three-Stage Treatment Concept.Journal of clinical medicine · 2024Review
- Efficacy and Safety of Spinal Collagen Mesotherapy in Patients with Chronic Low Back Pain in a Three-Month Follow-Up-Retrospective Study.Journal of clinical medicine · 2024Article
- Effects of Intradermal Therapy (Mesotherapy) on Bilateral Cervicobrachial Pain.Journal of personalized medicine · 2024Article
- Neck Pain in Fibromyalgia: Treatment with Exercise and Mesotherapy.Biomedicines · 2023Article
- Clinical features of mesotherapy-associated non-tuberculous mycobacterial infections: A systematic review.International journal of women's dermatology · 2022Article
- Multiple session mesotherapy for management of coxofemoral osteoarthritis pain in 10 working dogs: A case series.The Canadian veterinary journal = La revue veterinaire canadienne · 2022Article
- A Call to Action by the Italian Mesotherapy Society on Scientific Research.Drug design, development and therapy · 2021Review
- Efficacy of Piroxicam Mesotherapy in Treatment of Knee Osteoarthritis: A Randomized Clinical Trial.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects.TheScientificWorldJournal · 2020Review
- Mesotherapy in the treatment of musculoskeletal pain in rehabilitation: the state of the art.Journal of pain research · 2019Review
- International Survey Regarding the Use of Rehabilitation Modalities in Horses.Frontiers in veterinary science · 2018Article
- Therapeutic Effectiveness and Safety of Mesotherapy in Patients with Osteoarthritis of the Knee.Evidence-based complementary and alternative medicine : eCAM · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mesotherapy is the injection of active substances into the surface layer of the skin. This method allows a slower spread, higher levels, and longer lasting effects of drugs in the tissues underlying the site of injection (skin, muscle, and joint) compared with those following intramuscular injection. This technique is useful when a local pharmacological effect is required and relatively high doses of drug in the systemic circulation are not. Mesotherapy should only be undertaken following a complete clinical workup and subsequent diagnosis. Encouraging results have been reported in randomized, controlled clinical trials and in observational studies involving patients with various forms of musculoskeletal pain. Recommendations by experts from the Italian Society of Mesotherapy for appropriate use of mesotherapy in musculoskeletal pain and an algorithm for treating localized painful conditions are provided.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.