ArticleFrontiers in plant science2012
Proteomic investigations of complex I composition: how to define a subunit?
Article in Frontiers in plant science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- PCIS1 is an essential factor in mitochondrial RNA splicing and complex I biogenesis, with distinct effects in null and downregulated mutants.Plant cell reports · 2026Article
- A ferredoxin bridge connects the two arms of plant mitochondrial complex I.The Plant cell · 2021Article
- OsPPR939, a nad5 splicing factor, is essential for plant growth and pollen development in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Article
- Mitochondrial Pentatricopeptide Repeat Protein, EMB2794, Plays a Pivotal Role in NADH Dehydrogenase Subunit nad2 mRNA Maturation in Arabidopsis thaliana.Plant & cell physiology · 2020Article
- A Mitochondrial LYR Protein Is Required for Complex I Assembly.Plant physiology · 2019Article
- Different Types Domains are Present in Complex I from Immature Seeds and of CA Adult Plants in Arabidopsis thaliana.Plant & cell physiology · 2019Article
- Respiratory chain Complex I of unparalleled divergence in diplonemids.The Journal of biological chemistry · 2018Article
- Targeted cleavage ofCommunications biology · 2018Article
- Control of organelle gene expression by the mitochondrial transcription termination factor mTERF22 in Arabidopsis thaliana plants.PloS one · 2018Article
- Transformation of nad7 into the nuclear genome rescues the slow growth3 mutant in Arabidopsis.RNA biology · 2018Article
- Respiratory complex I and embryo development.Journal of experimental botany · 2016Article
- L-Galactono-1,4-lactone dehydrogenase is an assembly factor of the membrane arm of mitochondrial complex I in Arabidopsis.Plant molecular biology · 2016Article
- Complete Mitochondrial Complex I Deficiency Induces an Up-Regulation of Respiratory Fluxes That Is Abolished by Traces of Functional Complex I.Plant physiology · 2015Article
- The SLOW GROWTH3 Pentatricopeptide Repeat Protein Is Required for the Splicing of Mitochondrial NADH Dehydrogenase Subunit7 Intron 2 in Arabidopsis.Plant physiology · 2015Article
- The Pentatricopeptide Repeat Proteins TANG2 and ORGANELLE TRANSCRIPT PROCESSING439 Are Involved in the Splicing of the Multipartite nad5 Transcript Encoding a Subunit of Mitochondrial Complex I.Plant physiology · 2014Article
- 3D Gel Map of Arabidopsis Complex I.Frontiers in plant science · 2013Article
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1 author.
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Abstract
Complex I is present in almost all aerobic species. Being the largest complex of the respiratory chain, it has a central role in energizing biological membranes and is essential for many organisms. Bacterial complex I is composed of 14 subunits that are sufficient to achieve the respiratory functions. Eukaryotic enzymes contain orthologs of the 14 bacterial subunits and around 30 additional subunits. This complexity suggests either that complex I requires more stabilizing subunits in mitochondria or that it fulfills additional functions. In many organisms recent work on complex I concentrated on the determination of its exact composition. This review summarizes the work done to elucidate complex I composition in the model plant Arabidopsis and proposes a model for the organization of its 44 confirmed subunits. The comparison of the different studies investigating the composition of complex I across species identifies sample preparation for the proteomic analysis as critical to differentiate between true subunits, assembly factors, or proteins associated with complex I. Coupling comparative proteomics with biochemical or genetic studies is thus required to define a subunit and its function within the complex.
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