Evidence map›Paper›PMID 22654558›Full record

ArticleCurrent genomics2011

Employing genetic markers to improve diagnosis of thyroid tumor fine needle biopsy.

Janete M Cerutti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer.Thyroid : official journal of the American Thyroid Association · 2015
    Guideline
  3. Article
  4. Frontiers in cell and developmental biology · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Janete M CeruttiGenetic Bases of Thyroid Tumor Laboratory, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Federal University of São Paulo, SP, Brazil.

Funding

Preoperative and follow-up tests for thyroid tumorsR33CA113461 · NCI · JOHNS HOPKINS UNIVERSITY · PI RIGGINS, GREGORY JOSEPH · 2009 to 2010
$555k
Preoperative and follow-up tests for thyroid tumorsR21CA113461 · NCI · JOHNS HOPKINS UNIVERSITY · PI RIGGINS, GREGORY JOSEPH · 2006 to 2006
$240k
NCI NIH HHS R21 CA113461NCI NIH HHS R33 CA113461
6 · The paper itself

Abstract

Fine-Needle Aspiration (FNA) is the most widely used and cost-effective preoperative test for the initial evaluation of a thyroid nodule, although it has limited diagnostic accuracy for several types of tumors. Patients will often receive cytological report of indeterminate cytology and are referred to surgery for a more accurate diagnosis. An improved test would help physicians rapidly focus treatment on true malignancies and avoid some unnecessary treatment of benign tumors. This review will discuss current molecular markers that may improve thyroid nodule diagnosis.

Indexed as

C1orf24.FNAfollicular thyroid adenomaFollicular thyroid carcinomaindeterminate noduleITM1molecular markers

Identifiers

PMID22654558
PMCPMC3271311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.