ArticleCurrent genomics2011
The genetic basis of graves' disease.
Article in Current genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- Exploring antigenic variation in autoimmune endocrinopathy.Frontiers in immunology · 2025Review
- COVID-19 vaccine-induced autoimmune hyperthyroidism: Graves' disease.Frontiers in immunology · 2025Review
- Article
- Graves' Disease in Children: An Update.Clinical medicine insights. Endocrinology and diabetes · 2023Review
- Phenome of coeliac disease vs. inflammatory bowel disease.Scientific reports · 2022Article
- Actual Associations between HLA Haplotype and Graves' Disease Development.Journal of clinical medicine · 2022Article
- Genetic Association Study of IL2RA, IFIH1, and CTLA-4 Polymorphisms With Autoimmune Thyroid Diseases and Type 1 Diabetes.Frontiers in pediatrics · 2020Article
- Aberrant Histone Methylation in Patients with Graves' Disease.International journal of endocrinology · 2019Article
- DNA methylation in ELOVL2 and C1orf132 correctly predicted chronological age of individuals from three disease groups.International journal of legal medicine · 2018Article
- Biomarker identification of thyroid associated ophthalmopathy using microarray data.International journal of ophthalmology · 2018Article
- Variable Effects of Dietary Selenium in Mice That Spontaneously Develop a Spectrum of Thyroid Autoantibodies.Endocrinology · 2017Article
- Is Graves' disease a primary immunodeficiency? New immunological perspectives on an endocrine disease.BMC medicine · 2017Review
- High-level intrathymic thyrotrophin receptor expression in thyroiditis-prone mice protects against the spontaneous generation of pathogenic thyrotrophin receptor autoantibodies.Clinical and experimental immunology · 2017Article
- Predictive Value of Gene Polymorphisms on Recurrence after the Withdrawal of Antithyroid Drugs in Patients with Graves' Disease.Frontiers in endocrinology · 2017Review
- Differences in Gene-Gene Interactions in Graves' Disease Patients Stratified by Age of Onset.PloS one · 2016Article
- Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma.Oncogenesis · 2015Article
- TSHR intronic polymorphisms (rs179247 and rs12885526) and their role in the susceptibility of the Brazilian population to Graves' disease and Graves' ophthalmopathy.Journal of endocrinological investigation · 2015Article
- Complicating autoimmune diseases in myasthenia gravis: a review.Autoimmunity · 2015Review
- Breaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunity.Endocrine reviews · 2014Review
- High frequency of the X-chromosome inactivation in young female patients with high-grade glioma.Diagnostic pathology · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presented comprehensive review of current knowledge about genetic factors predisposing to Graves' disease (GD) put emphasis on functional significance of observed associations. In particular, we discuss recent efforts aimed at refining diseases associations found within the HLA complex and implicating HLA class I as well as HLA-DPB1 loci. We summarize data regarding non-HLA genes such as PTPN22, CTLA4, CD40, TSHR and TG which have been extensively studied in respect to their role in GD. We review recent findings implicating variants of FCRL3 (gene for FC receptor-like-3 protein), SCGB3A2 (gene for secretory uteroglobin-related protein 1- UGRP1) as well as other unverified possible candidate genes for GD selected through their documented association with type 1 diabetes mellitus: Tenr-IL2-IL21, CAPSL (encoding calcyphosine-like protein), IFIH1(gene for interferon-induced helicase C domain 1), AFF3, CD226 and PTPN2. We also review reports on association of skewed X chromosome inactivation and fetal microchimerism with GD. Finally we discuss issues of genotype-phenotype correlations in GD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.