Evidence map›Paper›PMID 22654498›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2012

Successful salvage therapy of Fusarium endophthalmitis secondary to keratitis: an interventional case series.

Grant M Comer, Maxwell S Stem, Stephen J Saxe

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Progression of Sclerouveitis to EndogenousCase reports in ophthalmological medicine · 2024
    Article
  3. Article
  4. Article
  5. Indications and techniques of endoscope assisted vitrectomy.Journal of ophthalmic & vision research · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Grant M ComerUniversity of Michigan, Department of Ophthalmology and Visual Sciences, Ann Arbor, MI, USA.
Maxwell S Stem
Stephen J Saxe
University of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe a combination of treatment modalities used for the successful eradication of Fusarium endophthalmitis.

designInterventional case series.

participantsThree consecutive patients with keratitis-associated Fusarium endophthalmitis.

methodsAfter failure of traditional management options, a combination of intravitreal and long-term, high-dose systemic voriconazole, topical antifungal medications, and surgical intervention, with penetrating keratoplasty, lensectomy, and endoscopic-guided pars plana vitrectomy, was administered to each patient.

resultsAll three cases achieved full resolution of the infection, with a final Snellen visual acuity score of 20/50 to 20/70.

conclusionsAn aggressive combination of therapeutic modalities, including the removal of subiris abscesses, might be needed for the successful resolution of Fusarium endophthalmitis.

Indexed as

endophthalmitisfungalfusariumkeratitiskeratoplastyvoriconazole

Identifiers

PMID22654498
PMCPMC3363314
OpenAlexW2063048156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.