SynthesisWorld journal of gastroenterology2012
Association between body mass index and erosive esophagitis: a meta-analysis.
Synthesis in World journal of gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Association between body mass index at different levels and risk of gastroesophageal reflux disease: a systematic review with dose-response meta-analysis.Frontiers in physiology · 2025Pooled it
- Weight Gain Is Associated With Decreased Treatment Response to Dietary Therapy in Adults With Eosinophilic Esophagitis.Gastro hep advances · 2025Article
- Medication use and risk of reflux oesophagitis.BMJ open gastroenterology · 2024Article
- Comparison of RDQ and GERDQ for Predicting Erosive Esophagitis in Patients with Typical GERD Symptoms.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Article
- Higher Body Mass Index Is Associated With Decreased Treatment Response to Topical Steroids in Eosinophilic Esophagitis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Article
- Role of Obesity, Physical Exercise, Adipose Tissue-Skeletal Muscle Crosstalk and Molecular Advances in Barrett's Esophagus and Esophageal Adenocarcinoma.International journal of molecular sciences · 2022Review
- Association between the body mass index, waist circumference, and body fat percentage with erosive esophagitis in adults with obesity after sleeve gastrectomy.F1000Research · 2022Article
- Visceral Obesity, Metabolic Syndrome, and Esophageal Adenocarcinoma.Frontiers in oncology · 2021Review
- The association between metabolic syndrome and erosive esophagitis: A systematic review and meta-analysis.EXCLI journal · 2021Review
- Potential involvement of adiponectin in obesity-associated erosive esophagitis.Journal of clinical biochemistry and nutrition · 2020Article
- Effect of Weight Changes on the Development of Erosive Esophagitis.Korean journal of family medicine · 2020Article
- Weight Loss as a Nonpharmacologic Strategy for Erosive Esophagitis: A 5-Year Follow-up Study.Gut and liver · 2018Article
- Prevalence and Predictors of Silent Gastroesophageal Reflux Disease in Patients with Hypertension.Gastroenterology research and practice · 2018Article
- Relationship between obesity and development of erosive reflux disease: A mediation analysis of the role of cardiometabolic risk factors.Scientific reports · 2017Article
- Gastrointestinal Complications of Obesity.Gastroenterology · 2017Review
- Factors associated with complicated erosive esophagitis: A Japanese multicenter, prospective, cross-sectional study.World journal of gastroenterology · 2017Observational
- Is Metabolic Syndrome Considered to Be a Risk Factor for Gastroesophageal Reflux Disease (Non-Erosive or Erosive Esophagitis)?: A Systematic Review of the Evidence.Iranian Red Crescent medical journal · 2016Review
- Indications for Surgery for Obesity and Weight-Related Diseases: Position Statements from the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO).Obesity surgery · 2016Article
- Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association.Gastroenterology research and practice · 2016Article
- Different risk factors between reflux symptoms and mucosal injury in gastroesophageal reflux disease.The Kaohsiung journal of medical sciences · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo conduct a meta-analysis to estimate the determinants of the association between erosive esophagitis (EE) and body mass index (BMI).
methodsWe identified the studies using PubMed. Studies were selected for analysis based on certain inclusion and exclusion criteria. Data were extracted from each study on the basis of predefined items. Meta-analyses were performed to verify the risk factors, such as obesity and gender.
resultsTwenty-one studies were included in this systematic review. These studies demonstrated an association between increasing BMI and the presence of EE [95% confidence interval (CI): 1.35-1.88, overweight, odds ratio (OR) = 1.60, P value homogeneity = 0.003, 95% CI: 1.65-2.55, obese, OR = 2.05, P < 0.01]. The heterogeneity disappeared by stratifying for gender. No publication bias was observed in this meta-analysis by the Egger method.
conclusionThis analysis demonstrates a positive association between BMI and the presence of EE, especially in males. The risk seems to progressively increase with increasing weight.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.